皮质-杏仁核回路中条件性味觉厌恶的编码。
Encoding of Conditioned Taste Aversion in Cortico-Amygdala Circuits.
机构信息
Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland; Gonda Multidisciplinary Brain Research Center, Bar Ilan University, Ramat Gan 5290002, Israel; Sagol Department of Neurobiology, University of Haifa, Haifa 3498838, Israel.
Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland.
出版信息
Cell Rep. 2018 Jul 10;24(2):278-283. doi: 10.1016/j.celrep.2018.06.053.
Avoidance of potentially toxic food by means of conditioned taste aversion is critical for survival of many animals. However, the underlying neuronal mechanisms are poorly understood. Here, using two-photon calcium imaging of defined gustatory cortex neurons in vivo, we show that conditioned taste aversion dynamically shifts neuronal population coding by stimulus-specific recruitment of neurons that project to the basolateral amygdala.
通过条件性味觉厌恶来避免潜在的有毒食物对许多动物的生存至关重要。然而，其潜在的神经元机制仍不清楚。在这里，我们使用双光子钙成像技术对体内特定的味觉皮层神经元进行研究，结果表明，条件性味觉厌恶通过特定于刺激的投射到基底外侧杏仁核的神经元的募集，动态地改变了神经元群体的编码。
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