Cheng J W, Wei R L
Department of Ophthalmology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Zhonghua Yan Ke Za Zhi. 2018 Jul 11;54(7):488-490. doi: 10.3760/cma.j.issn.0412-4081.2018.07.003.
Dysthyroid optic neuropathy (DON) is the most common cause of visual loss in thyroid associated ophthalmopathy, for which steroid pulse therapy and orbital decompression are the common treatments currently. While steroid pulse therapy was recommended as the first-choice for DON, orbital decompression remained as an indispensable therapy although controversies on such treatment still exist. The mechanism, approaches and outcomes of orbital decompression, as well as its advantages and disadvantages over steroid pulse therapy were retrospectively reviewed, and it was suggested that the combination therapy of steroid pulse therapy and surgical decompression might be the better choice for the treatment of DON. .
甲状腺功能异常性视神经病变(DON)是甲状腺相关性眼病导致视力丧失的最常见原因,目前针对该疾病的常用治疗方法是类固醇脉冲疗法和眼眶减压术。虽然类固醇脉冲疗法被推荐为DON的首选治疗方法,但尽管对于这种治疗方法仍存在争议,眼眶减压术仍是不可或缺的治疗手段。本文回顾性分析了眼眶减压术的机制、方法、疗效以及与类固醇脉冲疗法相比的优缺点,结果表明类固醇脉冲疗法与手术减压联合治疗可能是治疗DON的更佳选择。