Copeland L J, Sneige N, Gershenson D M, Saul P B, Stringer C A, Seski J C
Obstet Gynecol. 1986 Jan;67(1):115-20.
Five cases of adenoid cystic carcinoma of the Bartholin gland, a rare vulvar tumor, are reviewed with respect to clinical and pathological characteristics. Histologic transition from normal Bartholin gland to adenoid cystic carcinoma was evident in two cases. Two patients developed the tumor in association with pregnancy. Local recurrences are common and may precede distant metastases, pulmonary being the most common. Patients with repetitive local recurrence or pulmonary metastases may have slowly progressive disease and survive for many years. This is reflected in the disparity between the progression-free interval and survival curves. The recommended primary treatment is wide local excision, obtaining clear margins, and an ipsilateral inguinal lymphadenectomy.
本文回顾了5例巴氏腺腺样囊性癌（一种罕见的外阴肿瘤）的临床和病理特征。在2例病例中，可见从正常巴氏腺到腺样囊性癌的组织学转变。2例患者在妊娠期间发生肿瘤。局部复发很常见，可能先于远处转移，肺是最常见的转移部位。反复局部复发或肺转移的患者可能患有缓慢进展性疾病，并存活多年。这反映在无进展生存期和生存曲线之间的差异上。推荐的主要治疗方法是广泛局部切除，确保切缘阴性，并进行同侧腹股沟淋巴结清扫术。
