Kikuchi Hirokazu, Fujii Toshikatsu
Department of Neurology, Tohoku Medical and Pharmaceutical University.
Brain Nerve. 2018 Jul;70(7):783-794. doi: 10.11477/mf.1416201079.
The medial temporal lobe was identified as an important neural structure in human memory by the advent of patient H.M., who suffered from severe amnesia caused by bilateral medial temporal lobectomy. Dozens of neuropsychological study of H.M. led to the classification of human memory into declarative and non-declarative memory, as well as short-term and long-term memory. The medial temporal lobe subserves declarative memory and long-term memory. It also plays an important role especially in the process of memory consolidation. The psychological and neurological mechanisms of the consolidation process can be investigated through the study of retrograde amnesia and epileptic amnesia.
内侧颞叶被认定为人类记忆中的一个重要神经结构,这一发现源于患者H.M.的出现,他因双侧内侧颞叶切除术而患有严重失忆症。对H.M.进行的数十项神经心理学研究促使人类记忆被分类为陈述性记忆和非陈述性记忆,以及短期记忆和长期记忆。内侧颞叶负责陈述性记忆和长期记忆。它在记忆巩固过程中也发挥着重要作用。可以通过对逆行性失忆症和癫痫性失忆症的研究来探究巩固过程的心理和神经机制。