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[About the clinical picture after circumscribed failure of the ammonium cortex on both sides; a contribution to the knowledge of the function of the ammon horn].[关于双侧铵皮质局限性衰竭后的临床症状；对铵角功能认识的一项贡献]
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An animal model of amnesia that uses Receiver Operating Characteristics (ROC) analysis to distinguish recollection from familiarity deficits in recognition memory.一种遗忘症动物模型，使用接收者操作特征 (ROC) 分析来区分识别记忆中回忆和熟悉度缺陷。
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Perception and the medial temporal lobe: evaluating the current evidence.感知与内侧颞叶：评估当前证据
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The legacy of patient H.M. for neuroscience.患者H.M. 对神经科学的贡献。
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Constructing receiver operating characteristics (ROCs) with experimental animals: cautionary notes.用实验动物构建受试者工作特征曲线（ROC）：注意事项。
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Perirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks.嗅周皮质在构型物体识别和知觉奇特性任务中解决特征模糊性问题。
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识别记忆和内侧颞叶遗忘的动物模型：历史和当前问题。

An animal model of recognition memory and medial temporal lobe amnesia: history and current issues.

机构信息

Veterans Affairs Medical Center, San Diego, 92161, USA.

出版信息

Neuropsychologia. 2010 Jul;48(8):2234-44. doi: 10.1016/j.neuropsychologia.2010.02.004. Epub 2010 Feb 7.

DOI:10.1016/j.neuropsychologia.2010.02.004
PMID:20144894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2975590/
Abstract

The medial temporal lobe includes a system of anatomically connected structures that are essential for declarative memory (conscious memory for facts and events). A prominent form of declarative memory is recognition memory (the ability to identify a recently encountered item as familiar). Recognition memory has been frequently assessed in humans and in the experimental animal. This article traces the successful development of an animal model of human medial temporal lobe amnesia, which eventually identified the structures in the medial temporal lobe important for memory. Attention is given to two prominent behavioral paradigms (delayed nonmatching to sample and tests of spontaneous novelty preference).

摘要

内侧颞叶包括一个在解剖上相互连接的结构系统，对于陈述性记忆（对事实和事件的有意识记忆）至关重要。陈述性记忆的一种突出形式是识别记忆（识别最近遇到的项目是否熟悉的能力）。识别记忆已在人类和实验动物中得到广泛评估。本文追溯了人类内侧颞叶遗忘动物模型的成功发展，该模型最终确定了内侧颞叶中对记忆重要的结构。本文重点介绍了两个突出的行为范式（延迟不匹配样本和自发新颖性偏好测试）。