Preti Antonio, Raballo Andrea, Kotzalidis Georgios D, Scanu Rosanna, Muratore Tamara, Gabbrielli Mersia, Tronci Debora, Masala Carmelo, Petretto Donatella Rita, Carta Mauro G
Center of Liaison Psychiatry and Psychosomatics, University Hospital, University of Cagliari, Cagliari, Italy.
Section on Clinical Psychology, Department of Education, Psychology, Philosophy, University of Cagliari, Cagliari, Italy.
Clin Pract Epidemiol Ment Health. 2018 May 23;14:120-131. doi: 10.2174/1745017901814010154. eCollection 2018.
Diagnosing people during the prodromal phase of an incipient psychosis can improve the chance of better outcome. In busy clinical settings, the ideal tool is a brief, easy-to-complete self-report questionnaire.
To test the psychometric properties of the Italian version of one of the most used screening tools for the identification of the risk of psychosis, the Prodromal Questionnaire-Brief (PQ-B).
Cross-sectional design. A convenience sample of college students was enrolled snowball procedure (n=243; men: 45%). After understanding and signing the consent form, the participants received a booklet containing the following questionnaires: the 21-item Prodromal Questionnaire-Brief (PQ-B); the 12-item General Health Questionnaire (GHQ-12), and the 74-item Schizotypal Personality Questionnaire (SPQ). Receiver operating characteristic (ROC) analysis was used to assess the capacity of the PQ-B to identify individuals at risk of psychosis as independently defined based on the combination of GHQ-12 and SPQ thresholds.
The Italian version of the PQ-B revealed good internal consistency, test-retest reliability, and adequate convergent and divergent validity. The Youden method retrieved a cut-off = 7 for the PQ-B frequency score and a cut-off = 22 for the PQ-B distress score. Both PQ-B scores had a perfect (99%) negative predictive value.
The PQ-B is a promising screening tool in two-stage protocols. The major advantage of the PQ-B is to exclude cases that are unlikely to be at risk of psychosis.
在早期精神病的前驱期对患者进行诊断可提高获得更好预后的机会。在繁忙的临床环境中，理想的工具是一份简短、易于完成的自我报告问卷。
测试意大利语版的前驱期问卷简表（PQ-B），这是最常用的用于识别精神病风险的筛查工具之一的心理测量特性。
采用横断面设计。通过滚雪球程序招募了一个大学生便利样本（n = 243；男性占45%）。在理解并签署同意书后，参与者收到一本包含以下问卷的小册子：21项的前驱期问卷简表（PQ-B）；12项的一般健康问卷（GHQ-12），以及74项的分裂型人格问卷（SPQ）。采用受试者工作特征（ROC）分析来评估PQ-B根据GHQ-12和SPQ阈值组合独立定义的识别精神病风险个体的能力。
意大利语版的PQ-B显示出良好的内部一致性、重测信度以及充分的收敛效度和区分效度。约登方法得出PQ-B频率得分的临界值 = 7，PQ-B痛苦得分的临界值 = 22。两个PQ-B得分均具有完美（99%）的阴性预测值。
PQ-B在两阶段方案中是一种很有前景的筛查工具。PQ-B的主要优势在于排除不太可能有精神病风险的病例。
