体力活动不会降低主动脉瓣狭窄的发生率。
Physical Activity Does Not Reduce Aortic Valve Stenosis Incidence.
机构信息
Center for Molecular Medicine, Department of Medicine, Karolinska Institutet.
Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet.
出版信息
Circ J. 2018 Aug 24;82(9):2372-2374. doi: 10.1253/circj.CJ-18-0598. Epub 2018 Jul 12.
BACKGROUND
Physical activity is associated with lower risk of coronary and cerebrovascular disease but its potential role in prevention of aortic valve stenosis (AVS) is unclear.
METHODS AND RESULTS
We investigated whether physical activity influences AVS risk in a cohort of 69,288 adults. During a mean follow-up of 15.3 years, 1,238 AVS cases were diagnosed. No associations were observed between AVS and walking/bicycling (≥1 h/day vs. almost never: hazard ratio 0.92, 95% CI 0.74-1.15) or exercise (≥4 hs/week vs. <1 h/week: hazard ratio 1.18, 95% CI 0.97-1.43).
CONCLUSIONS
Physical activity did not reduce the incidence of AVS.
背景
身体活动与较低的冠心病和脑血管疾病风险相关，但它在预防主动脉瓣狭窄（AVS）方面的潜在作用尚不清楚。
方法和结果
我们调查了身体活动是否会影响 69288 名成年人队列中的 AVS 风险。在平均 15.3 年的随访期间，诊断出 1238 例 AVS 病例。在 AVS 与步行/骑自行车（每天≥1 小时与几乎从不：风险比 0.92，95%CI0.74-1.15）或运动（每周≥4 小时与每周<1 小时：风险比 1.18，95%CI0.97-1.43）之间未观察到相关性。
结论
身体活动并未降低 AVS 的发病率。
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