家猫多中心性基底鳞状细胞癌中猫乳头瘤病毒2型的检测
Detection of Felis catus papillomavirus type 2 within multicentric basosquamous carcinoma in a domestic cat.
作者信息
Oh Ye-In, Cheon Doo-Sung, Lee Jung-Keun, Choi Mi-Hyun, Hwang Sun-Young, Kim Hyun-Wook, Kang Byung-Jae, Youn Hwa-Young
机构信息
Haemaru Referral Animal Hospital, Seongnam-si 13590, Republic of Korea.
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
出版信息
J Vet Med Sci. 2018 Sep 26;80(9):1445-1449. doi: 10.1292/jvms.17-0702. Epub 2018 Jul 11.
A 12-year-old neutered male domestic shorthair cat was presented with a 3-year history of multiple nonpruritic, ulcerated, plaque-like skin lesions but no other clinical signs. A systemic examination revealed mild lymphadenopathy. Histopathologic analysis of the skin lesions revealed multicentric basosquamous carcinoma (BSC). Immunohistochemical analysis, PCR, and sequencing detected Felis catus papillomavirus type 2 (FcaPV-2) within the tumors. As BSC is rare in cats, clinical behavior has not been established. To our knowledge, this is the first case report to demonstrate detection of FcaPV-2 within a BSC in a domestic cat.
一只12岁已绝育的雄性家养短毛猫，有3年多的病史，身上有多处非瘙痒性、溃疡状、斑块样皮肤病变，但无其他临床症状。全身检查发现轻度淋巴结病。对皮肤病变进行组织病理学分析，结果显示为多中心性基底鳞状细胞癌（BSC）。免疫组织化学分析、聚合酶链反应（PCR）和测序在肿瘤中检测到了猫乳头瘤病毒2型（FcaPV-2）。由于BSC在猫中较为罕见，其临床行为尚未明确。据我们所知，这是第一例在家养猫的BSC中检测到FcaPV-2的病例报告。
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