Munday John S, Thomson Neroli A, Luff Jennifer A
Pathobiology, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.
Pathobiology, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.
Vet J. 2017 Jul;225:23-31. doi: 10.1016/j.tvjl.2017.04.018. Epub 2017 May 3.
Papillomaviruses (PVs) cause disease in both dogs and cats. In dogs, PVs are thought to cause oral papillomatosis, cutaneous papillomas and canine viral pigmented plaques, whereas PVs have been rarely associated with the development of oral and cutaneous squamous cell carcinomas in this species. In cats, PVs are currently thought to cause oral papillomas, feline viral plaques, Bowenoid in situ carcinomas and feline sarcoids. Furthermore, there is increasing evidence that PVs may also be a cause of cutaneous squamous cell carcinomas and basal cell carcinomas in cats. These diseases are discussed in this review. Additionally, there is a brief overview of PV biology, including how these viruses cause disease. Diagnostic techniques and possible methods to prevent PV infection are also discussed.
乳头瘤病毒(PVs)可导致犬猫发病。在犬类中,PVs被认为会引起口腔乳头瘤病、皮肤乳头瘤和犬病毒性色素沉着斑,而在该物种中,PVs与口腔和皮肤鳞状细胞癌的发生很少相关。在猫科动物中,目前认为PVs会引起口腔乳头瘤、猫病毒性斑块、鲍温样原位癌和猫肉瘤。此外,越来越多的证据表明,PVs也可能是猫皮肤鳞状细胞癌和基底细胞癌的病因。本文将对这些疾病进行讨论。此外,还简要概述了PV生物学,包括这些病毒如何引发疾病。文中还讨论了诊断技术以及预防PV感染的可能方法。