Gentamicin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of gentamicin, but their serum levels with three times daily dosages are far below those attained when treating newborn infections and systemic effects of gentamicin are unlikely. Older infants would be expected to absorb even less gentamicin. Because there is little variability in the milk gentamicin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Maternal use of an ear drop or eye drop that contains gentamicin presents little or no risk for the nursing infant.[1]
庆大霉素很少分泌到母乳中。新生儿显然会吸收少量庆大霉素，但每日三次给药时他们的血清水平远低于治疗新生儿感染时达到的水平，庆大霉素不太可能产生全身影响。预计较大婴儿吸收的庆大霉素会更少。由于在每日多次给药方案期间母乳中庆大霉素水平变化很小，根据给药时间安排母乳喂养对减少婴儿接触庆大霉素几乎没有益处。尚无关于每日单次给药方案的数据。监测婴儿是否有胃肠道菌群受影响的可能，如腹泻、念珠菌病（如鹅口疮、尿布疹），或罕见的粪便带血提示可能存在抗生素相关性结肠炎。母亲使用含庆大霉素的耳滴剂或眼药水对哺乳婴儿几乎没有风险。[1]
