Similar to other aminoglycoside antibiotics, streptomycin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of aminoglycosides, but serum levels are far below those attained when treating newborn infections and systemic effects of streptomycin are unlikely. Older infants would be expected to absorb even less streptomycin Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.
与其他氨基糖苷类抗生素相似，链霉素很少排泄到母乳中。新生儿显然会吸收少量氨基糖苷类药物，但血清水平远低于治疗新生儿感染时达到的水平，链霉素不太可能产生全身影响。年龄较大的婴儿预计吸收的链霉素更少。监测婴儿是否有对胃肠道菌群的可能影响，如腹泻、念珠菌病（如鹅口疮、尿布疹），或罕见的大便带血，提示可能存在抗生素相关性结肠炎。
