Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as temozolamide.[1] It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence. The manufacturer recommends withholding breastfeeding for 1 week after the last dose. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.
大多数资料认为,在母亲接受抗肿瘤药物治疗期间,尤其是使用替莫唑胺等烷化剂时,母乳喂养是禁忌的。[1] 在间歇治疗期间,适当暂停一段时间母乳喂养后,可能可以安全地进行母乳喂养。制造商建议在最后一剂药物后停止母乳喂养1周。化疗可能会对母乳的正常微生物群和化学组成产生不利影响。