Because there is no published experience with methamphetamine as a therapeutic agent during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. One expert recommends that amphetamines not be used therapeutically in nursing mothers.[1] Methamphetamine should not be used as a recreational drug by nursing mothers because it may impair their judgment and childcare abilities. Methamphetamine and its metabolite, amphetamine, are detectable in breastmilk and infant serum after abuse of methamphetamine by nursing mothers. However, these data are from random collections rather than controlled studies because of ethical considerations in administering recreational methamphetamine to nursing mothers. Other factors to consider are the possibility of positive urine tests in breastfed infants which might have legal implications, and the possibility of other harmful contaminants in street drugs. Breastfeeding is generally discouraged in mothers who are actively abusing amphetamines.[2–5] In mothers who abuse methamphetamine while nursing, withholding breastfeeding for 48 to 100 hours after the maternal use been recommended, although in many mothers methamphetamine is undetectable in breastmilk after an average of 72 hours from the last use.[6,7] It has been suggested that breastfeeding can be reinstated 24 hours after a negative maternal urine screen for amphetamines.[7]
由于目前尚无关于甲基苯丙胺作为哺乳期治疗药物的公开经验，因此可能更倾向于选择其他药物，尤其是在喂养新生儿或早产儿期间。一位专家建议，哺乳期母亲不应将苯丙胺用于治疗目的。[1] 哺乳期母亲不应将甲基苯丙胺用作消遣性药物，因为这可能会损害她们的判断力和育儿能力。哺乳期母亲滥用甲基苯丙胺后，母乳和婴儿血清中可检测到甲基苯丙胺及其代谢产物苯丙胺。然而，由于向哺乳期母亲施用消遣性甲基苯丙胺存在伦理考量，这些数据来自随机收集而非对照研究。其他需要考虑的因素包括母乳喂养婴儿尿液检测呈阳性可能产生的法律影响，以及街头毒品中存在其他有害污染物的可能性。对于正在积极滥用苯丙胺的母亲，通常不建议母乳喂养。[2 - 5] 对于在哺乳期间滥用甲基苯丙胺的母亲，建议在母亲使用后停止母乳喂养48至100小时，不过在许多母亲中，自上次使用平均72小时后母乳中就检测不到甲基苯丙胺了。[6,7] 有人建议，在母亲尿液苯丙胺筛查呈阴性24小时后可以恢复母乳喂养。[7]
