Acupuncture and acupressure at traditional Chinese medicine (TCM) sites used to treat low milk supply has been claimed to cause release of prolactin and oxytocin, although published studies have found mixed results regarding serum prolactin. A meta-analysis found that acupressure improved milk production and increased serum prolactin, but the quality and consistency of the studies was variable.[1] No serious adverse effects on milk production were seen among lactating women who received acupuncture or acupressure for postpartum sciatica.[1,2] Acupuncture has been well described in TCM for treating insufficient milk supply,[3,4] and has also been used in some Western countries.[5-7] Numerous studies found acupuncture at CV 17 (also referred to as Ren 17, Danzhong or Shanzong; located at the center of the sternum), SI 1 (Shaoze; on the little finger), ST 18 (Rugen; lower breast margins), Zusanli (ST 36), and Taichong (LR 3) to benefit women with a low postpartum milk supply.[8] These studies generally do not meet current evidence-based guidelines, partly because of the extreme difficulty in double-blinding and placebo-controlling acupuncture studies. However, 2 studies did find a better response to electroacupuncture applied at a traditional site for lactation stimulation (SI 1) than electroacupuncture applied at a site unrelated to milk production (LI 1). Electroacupuncture increased serum prolactin, infant weight and maternal perception of milk production more than domperidone alone.[9] None of the studies reported to date have made an attempt to optimize maternal nursing technique before acupuncture. Although less studied, acupressure at milk acupuncture sites has had similar effects.[10] Systematic reviews concluded that acupuncture and acupressure are effective in increasing serum prolactin and breastmilk volume, although study quality is critically low.[10-14] Acupressure combined with back massage increases serum prolactin and milk production more than either alone in one study.[15] The combination of acupuncture and Chinese herbal medicines appeared to be more effective in increasing lactation parameters than acupuncture alone.[14] Acupuncture therapy has been used to treat breastfeeding for milk stasis (engorgement). Randomized, nonblinded studies in an outpatient Swedish lactation clinic compared routine care (including oxytocin spray) to routine care plus acupuncture at 2 or 3 points for treating milk stasis.[16,17] A meta-analysis concluded that women who received acupuncture were less likely to develop an abscess, had less severe symptoms on day five, and had a lower rate of fever than women in the usual care group However, there is insufficient evidence from published trials to justify widespread implementation.[18] A survey of 50 Swedish maternity units in 2007 found that 60% of hospitals used acupuncture to treat milk stasis, 18% used acupuncture to treat mastitis, and 2.2% each used it for painful breastfeeding or to improve milk supply. The authors felt that this extensive use was not justified based on the limited evidence for most of these uses.[19] Acupuncture and acupressure have also been used successfully as a treatment for breast engorgement and pain.[11,20] Auricular therapy uses stimulation of acupoints on the ear corresponding to various anatomical sites and functions of the body for the diagnosis, treatment, and prevention of disease. All studies applied seeds to press on ear acupoints. Two systematic reviews on auricular therapy to increase milk supply have come to differing conclusions. One review found a positive effect on milk production, onset of lactation, serum prolactin, breast fullness, neonate states, and frequency of newborn urination and defecation.[21] A more recent review found varying efficacy between studies and poor methodology that did not allow for a definitive conclusion on efficacy as a galactogogue.[22] No adverse effects were reported in any studies. A newer additional small study found similar results.[23] A controlled study found that auricular acupressure may slightly increase the pain threshold some areas of the breast in nursing mothers.[24] A single-blind study found auriculotherapy to increase breastfeeding self-efficacy in the mothers of preterm infants and to increase infant weight gain at hospital discharge.[25]
中医穴位的针灸和指压疗法常用于治疗乳汁分泌不足,据称可促使催乳素和催产素释放,不过已发表的研究在血清催乳素方面结果不一。一项荟萃分析发现,指压疗法可改善乳汁分泌并提高血清催乳素水平,但这些研究的质量和一致性存在差异。[1] 接受针灸或指压治疗产后坐骨神经痛的哺乳期妇女中,未观察到对乳汁分泌有严重不良影响。[1,2] 针灸在中医中对治疗乳汁分泌不足已有详细记载,[3,4] 并且在一些西方国家也有应用。[5-7] 众多研究发现,针刺膻中穴(CV 17,也称任脉17、膻中或山宗,位于胸骨正中)、少泽穴(SI 1,在小指)、乳根穴(ST 18,乳房下缘)、足三里穴(ST 36)和太冲穴(LR 3)对产后乳汁分泌不足的女性有益。[8] 这些研究总体上不符合当前基于证据的指南,部分原因是针刺研究很难做到双盲和设置安慰剂对照。然而,有2项研究发现,在传统的促进泌乳穴位(少泽穴)进行电针治疗,比在与乳汁分泌无关的穴位(合谷穴,LI 1)进行电针治疗效果更好。与单独使用多潘立酮相比,电针可提高血清催乳素水平、增加婴儿体重并增强母亲对乳汁分泌的感知。[9] 迄今为止,尚无研究尝试在针刺前优化产妇的哺乳技巧。虽然研究较少,但在乳汁针灸穴位进行指压也有类似效果。[10] 系统评价得出结论,针灸和指压可有效提高血清催乳素水平和母乳量,不过研究质量极低。[10-14] 一项研究发现,指压结合背部按摩比单独使用指压或背部按摩更能提高血清催乳素水平和乳汁分泌量。[15] 针灸与中药联合使用在增加泌乳参数方面似乎比单独使用针灸更有效。[14] 针灸疗法已用于治疗哺乳期乳汁淤积(乳房胀痛)。瑞典一家门诊哺乳诊所的随机、非盲研究,将常规护理(包括催产素喷雾)与在2至3个穴位进行常规护理加针灸治疗乳汁淤积进行了比较。[16,17] 一项荟萃分析得出结论,接受针灸治疗的女性发生脓肿的可能性较小,在第5天症状较轻,发热率低于常规护理组的女性。然而,已发表试验的证据不足,无法证明可广泛应用。[18] 2007年对瑞典50个产科单位的一项调查发现,60%的医院使用针灸治疗乳汁淤积,18%使用针灸治疗乳腺炎,2.2%的医院分别将其用于治疗母乳喂养疼痛或改善乳汁分泌。作者认为,基于这些用途的证据有限,这种广泛使用是不合理的。[19] 针灸和指压也已成功用于治疗乳房胀痛和疼痛。[11,20] 耳穴疗法通过刺激耳部对应身体各个解剖部位和功能的穴位来诊断、治疗和预防疾病。所有研究均采用种子按压耳穴。两项关于耳穴疗法增加乳汁分泌的系统评价得出了不同结论。一项评价发现,对乳汁分泌、泌乳开始、血清催乳素、乳房胀满、新生儿状态以及新生儿排尿和排便频率有积极影响。[21] 一项更新的评价发现,不同研究的疗效各异,且方法学欠佳,无法就其作为催乳剂的疗效得出明确结论。[22] 所有研究均未报告不良反应。一项新的小型补充研究也得出了类似结果。[23] 一项对照研究发现,耳穴指压可能会略微提高哺乳期母亲乳房某些区域的疼痛阈值。[24] 一项单盲研究发现,耳穴疗法可提高早产母亲的母乳喂养自我效能,并增加出院时婴儿的体重。[25]