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肠易激综合征患者的生活质量与抑郁

Quality of life and depression in patients with irritable bowel syndrome.

作者信息

Kopczyńska Magdalena, Mokros Łukasz, Pietras Tadeusz, Małecka-Panas Ewa

机构信息

Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland.

Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland.

出版信息

Prz Gastroenterol. 2018;13(2):102-108. doi: 10.5114/pg.2018.75819. Epub 2018 May 16.

DOI:10.5114/pg.2018.75819
PMID:30002768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6040097/
Abstract

INTRODUCTION

While irritable bowel syndrome (IBS) is not life-threatening for most, it has enormous influence on quality of life (QOL) and mental health.

AIM

To evaluate the association between QOL and depressive symptoms in IBS patients.

MATERIAL AND METHODS

A total of 87 patients and 56 healthy subjects were enrolled consecutively. All participants were asked to complete self-administered questionnaires: an IBS-specific quality of life (IBS-QOL) questionnaire and the Beck Depression Inventory questionnaire (BDI).

RESULTS

Mean BDI score was higher in IBS group than in controls. IBS-QOL score was significantly lower in IBS patients compared to the control group, in all IBS-QOL domains: dysphoria (DY), interference with activity (IN), body image (BI), health worry (HW), food avoidance (FA), social relation (SR), and sexual (SX) and relationship (RL) issues. QOL DY, IN, and BI scores and overall score were significantly lower in women with IBS compared to men. We found that BDI score was significantly negatively correlated with IBS-QOL score in the domain of DY, IN, HW, FA, SR, and RL scores and overall QOL score. We also found a negative correlation between older age and health worry. RL and IN QOL scores represented the highest correlation with BDI score.

CONCLUSIONS

Irritable bowel syndrome is connected with impaired patient quality of life and high prevalence of depression with high correlation rate of both parameter scores. Assessment of depression and QOL should be provided during patient visits in outpatients clinics.

摘要

引言

虽然肠易激综合征（IBS）对大多数人来说并不危及生命，但它对生活质量（QOL）和心理健康有巨大影响。

目的

评估IBS患者生活质量与抑郁症状之间的关联。

材料与方法

连续纳入87例患者和56名健康受试者。所有参与者均被要求完成自我管理问卷：一份IBS特异性生活质量（IBS-QOL）问卷和贝克抑郁量表问卷（BDI）。

结果

IBS组的平均BDI得分高于对照组。与对照组相比，IBS患者的IBS-QOL得分在所有IBS-QOL领域均显著更低：烦躁不安（DY）、活动受限（IN）、身体形象（BI）、健康担忧（HW）、食物回避（FA）、社会关系（SR）以及性（SX）和关系（RL）问题。与男性相比，IBS女性患者的QOL DY、IN和BI得分以及总分显著更低。我们发现，在DY、IN、HW、FA、SR和RL得分领域以及总体QOL得分方面，BDI得分与IBS-QOL得分显著负相关。我们还发现年龄较大与健康担忧之间存在负相关。RL和IN QOL得分与BDI得分的相关性最高。

结论

肠易激综合征与患者生活质量受损以及抑郁症的高患病率相关，两个参数得分的相关率很高。在门诊患者就诊期间应进行抑郁和QOL评估。

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