Dark A J
Br J Ophthalmol. 1977 Jan;61(1):65-9. doi: 10.1136/bjo.61.1.65.
Corneal epithelial biopsies from two patients affected with asymptomatic bleb dystrophy were examined by light and electron microscopy. The basis of this disorder appears to be the deposition of a neutral mucopolysaccharide-protein complex as a continuous layer between the basement membrane and Bowman's layer. This material, although homogeneous in light microscopy, has a fine granular ultrastructure. It is friable, and in view of the apparent integrity of the basement membrane/hemidesmosome system it is suggested that the recurrent epithelial erosions which can occur in this disorder result from shearing of this layer. Fissures in the bleb material contain cells which may play a role in its degradation.
对两名患有无症状泡性营养不良的患者的角膜上皮活检组织进行了光镜和电镜检查。这种疾病的基础似乎是一种中性粘多糖 - 蛋白质复合物在基底膜和Bowman层之间作为连续层沉积。这种物质在光镜下虽然均匀，但具有精细的颗粒超微结构。它很脆，鉴于基底膜/半桥粒系统明显完整，提示这种疾病中可能发生的复发性上皮糜烂是由该层的剪切引起的。泡性物质中的裂隙含有可能在其降解中起作用的细胞。
