Deán-Ben X L, Razansky D
Institute for Biological and Medical Imaging, Helmholtz Center Munich, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.
Faculty of Medicine, Technical University of Munich, Ismaningerstrasse 22, 81675 Munich, Germany.
Photoacoustics. 2018 Jun 15;11:1-5. doi: 10.1016/j.pacs.2018.06.001. eCollection 2018 Sep.
Individual light pulses with durations in the nanosecond range are most often employed in biomedical optoacoustic imaging. In this excitation regime, ultra-wideband acoustic responses are generated from tissues that cannot be efficiently captured with ultrasound transducers having a limited detection bandwidth. Here, we analyse a narrowband optoacoustic signal excitation mechanism consisting of a tone-burst of multiple equally-delayed pulses. The signal generation efficiency of single-pulse versus tone-burst excitation is compared for normal light exposure levels in the linear optoacoustic signal generation regime as well as when considering non-linearities associated with temperature increase or absorption saturation. The signal-to-noise ratio of the excited signals is also experimentally compared using a highly-absorbing ink phantom.
在生物医学光声成像中,最常使用持续时间在纳秒范围内的单个光脉冲。在这种激发方式下,具有有限检测带宽的超声换能器无法有效捕获的组织会产生超宽带声学响应。在此,我们分析了一种由多个等延迟脉冲的短脉冲串组成的窄带光声信号激发机制。在光声信号线性产生机制下的正常光照水平以及考虑与温度升高或吸收饱和相关的非线性时,比较了单脉冲激发与短脉冲串激发的信号产生效率。还使用高吸收性墨水仿体对激发信号的信噪比进行了实验比较。