College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, P. R. China.
Chem Commun (Camb). 2018 Jul 26;54(61):8498-8501. doi: 10.1039/c8cc04615h.
We demonstrate a strategy for pH-programmable self-assembly of DNA nanostructures by taking advantage of the pH dependence of reverse Hoogsteen interactions for a triplex-helix molecular switch. This strategy is successfully applied to the construction of molecular logic gates and imaging of extracellular pH.
我们展示了一种通过利用反 Hoogsteen 相互作用的 pH 依赖性来实现 DNA 结构可编程自组装的策略，该策略用于构建三聚体-螺旋分子开关。该策略成功应用于构建分子逻辑门和检测细胞外 pH 值。
