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非处方药的重复用药及其他风险:药剂师的观点与经验

Double-Dosing and Other Dangers with Non-Prescription Medicines: Pharmacists' Views and Experiences.

作者信息

Gauld Natalie, Sullivan Tracey

机构信息

Natalie Gauld Ltd., P. O. Box 9349, Newmarket, Auckland 1149, New Zealand.

Independent Researcher, Wellington, New Zealand.

出版信息

Pharmacy (Basel). 2018 Jul 2;6(3):59. doi: 10.3390/pharmacy6030059.

Abstract

The aim of this paper was to explore pharmacists' views on reclassifications from pharmacy-only to general sales and their experiences with the supply of these medicines, in addition to pharmacists' views on the reclassification of the shingles vaccine and sildenafil to be available through 'accredited' pharmacists. New Zealand community pharmacists were surveyed in 2013 with a written questionnaire of six Likert-style or open-ended questions sent to Pharmacy Guild member pharmacies. The analysis involved descriptive statistics. Responses were received from 246 pharmacies. Two thirds of pharmacists supported the reclassification of the shingles vaccine and sildenafil, although 14% disagreed with the sildenafil reclassification. Over 90% of pharmacists disagreed with the reclassification of paracetamol and ibuprofen liquids, omeprazole, naproxen, and oxymetazoline from pharmacy-only medicine to general sales. This opinion was strongest for omeprazole. With liquid paracetamol and ibuprofen, pharmacists described consumer confusion with dosing, and particularly potentially doubling-up on liquid analgesics/antipyretics including using both prescription and non-prescription variants. Many reported giving safety advice frequently. Anti-inflammatories and omeprazole were also subject to potential double-dosing, as well as requests by consumers with contraindications, precautions, and drug interactions, and for inappropriate indications. Pharmacists described various interventions, including some that were potentially life-saving. Pharmacy availability of medicines provides the potential for intervention that would not happen in a general sales environment.

摘要

本文旨在探讨药剂师对于药品从仅在药店销售重新分类为一般销售的看法,以及他们在供应这些药品方面的经验,此外还包括药剂师对于带状疱疹疫苗和西地那非通过“认可”药剂师供应进行重新分类的看法。2013年,通过向新西兰药剂师公会会员药店发送一份包含六个李克特式或开放式问题的书面调查问卷,对社区药剂师进行了调查。分析采用描述性统计方法。共收到246家药店的回复。三分之二的药剂师支持带状疱疹疫苗和西地那非的重新分类,不过14%的药剂师不同意西地那非的重新分类。超过90%的药剂师不同意将对乙酰氨基酚和布洛芬口服液、奥美拉唑、萘普生以及羟甲唑啉从仅在药店销售的药品重新分类为一般销售药品。这种观点对于奥美拉唑最为强烈。对于对乙酰氨基酚和布洛芬口服液,药剂师提到消费者在用药剂量方面存在困惑,特别是可能会同时使用液体镇痛药/退热药,包括同时使用处方药和非处方药品种。许多药剂师报告经常提供安全建议。抗炎药和奥美拉唑也存在潜在的重复用药情况,以及有禁忌症、注意事项和药物相互作用的消费者提出的要求,还有针对不适当适应症的要求。药剂师描述了各种干预措施,包括一些可能挽救生命的措施。药品在药店可供购买提供了在一般销售环境中不会发生的干预可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/6165278/89f2fd67e36d/pharmacy-06-00059-g001.jpg

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