Angle Orthod. 2018 Nov;88(6):757-764. doi: 10.2319/101517-694.1. Epub 2018 Jul 13.
: The purpose of this three-dimensional (3D) study was to assess retrospectively the middle cranial fossa and central skull base of patients treated with the Herbst appliance (HA).
: 3D surface virtual models of 40 Class II, division 1 malocclusion patients were generated from cone-beam computed tomography (CBCT) acquired before treatment (T0) and after 8 months of HA treatment (T1). T0 and T1 3D models were superimposed volumetrically at the anterior cranial fossa. Twenty subjects who had been treated with the Herbst appliance (HAG) were compared to 20 subjects who were not treated orthopedically. The latter group served as a comparison control group (CG). Quantitative assessments of the location and directional changes were made with linear and angular measurements between anatomical landmarks. Qualitative assessments of the spatial behavior of the middle cranial fossa and central skull base relative to the anterior cranial fossa were displayed graphically for visualization with color maps and semitransparent overlays. Non-parametric tests were performed to compare the between the HAG and CG.
: Point-to-point linear measurements and skeletal rotation (pitch, roll, and yaw) changes were very small along the observational period and were not significantly different between HAG and CG. Visual analysis of color maps and overlays confirmed that no changes in the cranial base were associated with HA.
: HA therapy did not produce clinically significant changes in the middle cranial fossa and central skull base.
本三维（3D）研究旨在回顾性评估接受 Herbst 矫治器（HA）治疗的患者的中颅窝和颅底中部。
从治疗前（T0）和 HA 治疗 8 个月后（T1）获得的锥形束 CT（CBCT）生成 40 例 Class II 类，1 分类错牙合患者的 3D 表面虚拟模型。在颅前窝对 T0 和 T1 的 3D 模型进行体积叠加。将 20 例接受 Herbst 矫治器治疗的患者（HAG）与 20 例未接受正畸治疗的患者进行比较。后者作为对照组（CG）。使用解剖学标志之间的线性和角度测量对位置和方向变化进行定量评估。使用彩色地图和半透明叠加显示中颅窝和颅底中部相对于颅前窝的空间行为的定性评估。进行非参数检验以比较 HAG 和 CG 之间的差异。
沿观察期，点到点的线性测量和骨骼旋转（俯仰、滚转和偏航）变化非常小，并且在 HAG 和 CG 之间没有显著差异。彩色地图和叠加的直观分析证实，HA 治疗不会引起颅底的变化。
HA 治疗不会导致中颅窝和颅底中部发生临床显著变化。
