Sweeney Denise L, Wang Erica B, Austin Evan, Jagdeo Jared
J Drugs Dermatol. 2018 Jul 1;17(7):780-785.
As body contouring procedures have become more popular, post-procedural skin laxity is a concern. Non-invasive body contouring technologies may effectively reduce body fat, but modestly affect skin tightening.
To assess the efficacy and safety of a topical skin tightening agent in combination with hyperthermic diode laser lipolysis.
Herein, we describe five patients in which a skin tightening concentrate of 5% yeast extract, 2% hydrolyzed rice protein content, and 2.5% tripeptide was used after 1500-2100 J/cm2 of hyperthermic 1060 nm diode laser.
Overall, all patients had a subjective positive response and high satisfaction with the combined treatment results of improvement in skin laxity and fat reduction. In all five cases, patients demonstrated visible fat reduction and skin improvement on photographs taken between weeks 6-18 compared to baseline. Blinded investigators correctly predicted the order of the photographs based on treatment results. No adverse events were reported.
This case series demonstrated that a combined topical skin tightening concentrate with a hyperthermic laser lipolysis device may achieve improved aesthetic outcomes without adverse events. J Drugs Dermatol. 2018;17(7):780-785.
随着身体塑形手术越来越受欢迎，术后皮肤松弛成为一个令人担忧的问题。非侵入性身体塑形技术可以有效减少身体脂肪，但对皮肤紧致的作用有限。
评估一种局部皮肤紧致剂联合热二极管激光溶脂的疗效和安全性。
在此，我们描述了5例患者，在接受1500 - 2100 J/cm² 的1060 nm热二极管激光治疗后，使用了一种含有5%酵母提取物、2%水解大米蛋白和2.5%三肽的皮肤紧致浓缩液。
总体而言，所有患者对皮肤松弛改善和脂肪减少的联合治疗效果主观反应积极且满意度高。在所有5例患者中，与基线相比，在第6 - 18周拍摄的照片上可见脂肪减少和皮肤改善。不知情的研究人员根据治疗结果正确预测了照片的顺序。未报告不良事件。
该病例系列表明，局部皮肤紧致浓缩液与热激光溶脂设备联合使用可实现更好的美学效果且无不良事件。《药物皮肤病学杂志》。2018年；17(7):780 - 785。
