Zha Yi, Zhuang Jinfei, Du Yixia, Cai Jianqiu, Zheng Haihua
The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Nanjing Children's Hospital, Nanjing, Jiangsu, 210000, People's Republic of China.
BMC Ophthalmol. 2018 Jul 13;18(1):173. doi: 10.1186/s12886-018-0839-6.
To evaluate the peripapillary choroidal thickness (PPCT) in Chinese children aged 6 to 12 years old and to analyze correlative factors.
PPCT was measured with enhanced depth imaging optical coherence tomography (EDI-OCT) in 154 children (76 myopes and 78 emmetropia) aged 6 to 12 years, with spherical equivalent refractive errors between + 0.50 and - 5.50 diopters(D). Peripapillary choroidal imaging was performed using circular scans of a diameter of 3.4 mm around the optic disc. PPCT and the corresponding peripapillary retinal thickness (PPRT) were measured by EDI-OCT at nine positions: I, inferior; IN, inferonasal; IT, inferotemporal; N, nasal; T, temporal; S, superior; SN, superonasal; ST, superotemporal, and the Fovea Centralis.
The mean global PPCT was 165.80 ± 39.86 μm.The mean global PPRT was 101.47 ± 10.74 μm. The Inferior had the thinnest PPCT but the thickest PPRT (p < 0.001), while the Nasal had thickest PPCT but the thinnest PPRT (p < 0.001). Significant differences in RT between the myopic group and the emmetropic group were found at all positions except T, TS, S and the fovea. Myopic group had thinner choroidal thickness (CT) than that of emmetropic group at all measured positions. Choroidal thickness had negative relation with the corresponding retinal thickness, age and axial length.
The peripapillary choroid was thicker nasally and thinner inferiorly, while the peripapillary retina was thickest inferiorly and thinnest nasally. Myopic group had thinner PPCT. The axial length was found to be negatively correlated to PPCT.
评估6至12岁中国儿童的视乳头周围脉络膜厚度（PPCT）并分析相关因素。
采用增强深度成像光学相干断层扫描（EDI-OCT）对154名6至12岁儿童（76名近视儿童和78名正视儿童）进行PPCT测量，等效球镜屈光不正度数在+0.50至-5.50屈光度（D）之间。围绕视盘进行直径3.4 mm的环形扫描以获取视乳头周围脉络膜图像。通过EDI-OCT在九个位置测量PPCT和相应的视乳头周围视网膜厚度（PPRT）：I，下方；IN，鼻下方；IT，颞下方；N，鼻侧；T，颞侧；S，上方；SN，鼻上方；ST，颞上方，以及中央凹。
平均整体PPCT为165.80±39.86μm。平均整体PPRT为101.47±10.74μm。下方的PPCT最薄但PPRT最厚（p<0.001），而鼻侧的PPCT最厚但PPRT最薄（p<0.001）。除T、TS、S和中央凹外，近视组和正视组在所有位置的视网膜厚度（RT）均存在显著差异。在所有测量位置，近视组的脉络膜厚度（CT）均低于正视组。脉络膜厚度与相应的视网膜厚度、年龄和眼轴长度呈负相关。
视乳头周围脉络膜鼻侧较厚，下方较薄，而视乳头周围视网膜下方最厚，鼻侧最薄。近视组的PPCT较薄。发现眼轴长度与PPCT呈负相关。
