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头皮转移性血管肉瘤伴肺囊性病变:一例报告及肺囊性疾病综述

Metastatic Angiosarcoma of the Scalp Presenting with Cystic Lung Lesions: A Case Report and Review of Cystic Lung Diseases.

作者信息

Ajayi Antonette A, Commins Stephanie V, Clarke David E

机构信息

Internist at the Santa Clara Medical Center in CA.

Dean of Students at Tawa College in Wellington, New Zealand.

出版信息

Perm J. 2018;22:17-168. doi: 10.7812/TPP/17-168.

Abstract

INTRODUCTION

Angiosarcomas are rare, malignant vascular tumors that affect endothelial cells of blood vessels. Angiosarcomas most commonly occur on the scalp or face of elderly individuals and are highly aggressive, with a 5-year survival rate below 15%. Cutaneous angiosarcomas often metastasize to the lung, where they can present with cystic lesions, solid lesions, pneumothorax, and/or hemothorax.

CASE PRESENTATION

We report the case of an 83-year-old woman who presented with a scalp lesion, which was initially thought to be caused by scalp trauma but was later found to be an angiosarcoma. She initially refused any therapy for the tumor. She returned several months later with a cough and shortness of breath and was found to have multiple pulmonary cysts. She was treated with paclitaxel, but her tumor did not respond to the therapy and she died 2 months later.

DISCUSSION

We discuss the common presentation of cutaneous angiosarcomas and their tendency to metastasize to the lung and present as cystic lesions. We also review the common conditions that can cause cystic changes in the lungs.

摘要

引言

血管肉瘤是一种罕见的恶性血管肿瘤,影响血管内皮细胞。血管肉瘤最常发生于老年人的头皮或面部,具有高度侵袭性,5年生存率低于15%。皮肤血管肉瘤常转移至肺部,在肺部可表现为囊性病变、实性病变、气胸和/或血胸。

病例报告

我们报告一例83岁女性,其头皮出现病变,最初认为是由头皮外伤引起,但后来发现是血管肉瘤。她最初拒绝针对肿瘤的任何治疗。几个月后她因咳嗽和气短复诊,发现有多个肺囊肿。她接受了紫杉醇治疗,但肿瘤对治疗无反应,2个月后死亡。

讨论

我们讨论了皮肤血管肉瘤的常见表现及其转移至肺部并表现为囊性病变的倾向。我们还回顾了可导致肺部出现囊性改变的常见情况。

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