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儿童胸膜肺母细胞瘤:一例报告

Pleuropulmonary blastoma in children: a case report.

作者信息

Hashemi Azamsadat, Souzani Azadeh, Souzani Amineh, Keshavarzi Sara

机构信息

Hematology, Oncology and Genetic Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Iran J Cancer Prev. 2012 Spring;5(2):105-7.

Abstract

Pleuropulmonary Blastoma [PPB] is a very rare, highly aggressive and malignant tumor that originates from either the lungs or pleura. It occurs mainly in children aged less than five or six years. It has poor prognosis with three different subtypes: cystic [type I], combined cystic and solid [type II] and solid [type III]. PPB is treated with aggressive multimodal therapies including surgery and chemotherapy. We present a case of 3.5 years old boy with PPB type II successfully treated with complete surgical resection followed by neoadjuvant chemotherapy.

摘要

胸膜肺母细胞瘤(PPB)是一种非常罕见、具有高度侵袭性的恶性肿瘤,起源于肺或胸膜。它主要发生在五六岁以下的儿童中。其预后较差,有三种不同亚型:囊性(I型)、囊实性混合(II型)和实性(III型)。PPB采用包括手术和化疗在内的积极多模式治疗。我们报告一例3.5岁患II型PPB的男孩,经完整手术切除并辅以新辅助化疗后成功治愈。

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Pleuropulmonary blastoma: is prophylactic resection of congenital lung cysts effective?
Ann Thorac Surg. 2001 Aug;72(2):604-5. doi: 10.1016/s0003-4975(00)02539-x.
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