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从早期的开端到精细的工具：德国电生理学对心律失常介入治疗的贡献：德国心脏学会欢迎 2018 年在慕尼黑举行的 ESC。

From early beginnings to elaborate tools: contribution of German electrophysiology to the interventional treatment of cardiac arrhythmias : The German Cardiac Society welcomes ESC in Munich 2018.

机构信息

Department of Cardiology, Asklepios Klinik St. Georg, Lohmühlenstr. 5, 20099, Hamburg, Germany.

Asklepios Proresearch, Lohmühlenstr. 5, 20099, Hamburg, Germany.

出版信息

Clin Res Cardiol. 2018 Aug;107(Suppl 2):94-99. doi: 10.1007/s00392-018-1319-y. Epub 2018 Jul 13.

DOI:10.1007/s00392-018-1319-y
PMID:30006658
Abstract

Catheter ablation evolved from the early days of cardiac electrophysiology (EP), in which invasive electrophysiological studies were mainly a tool to find the correct diagnosis and to evaluate the most effective anti-arrhythmic drug for the patient. Today, catheter ablation is the most effective treatment option for patients suffering from supraventricular and ventricular arrhythmias. The understanding of cardiac arrhythmias and treatment strategies improved because of physicians and scientists from all over the world. The work of German cardiologists led to new achievements in the field of cardiac EP and catheter ablation. In this article, we summarize selective contributions of German EP centres in the field.

摘要

导管消融术起源于心脏电生理学（EP）的早期，在早期，侵入性电生理研究主要是一种寻找正确诊断和评估患者最有效抗心律失常药物的工具。如今，导管消融术是治疗室上性和室性心律失常患者的最有效治疗选择。由于来自世界各地的医生和科学家的努力，对心脏心律失常的理解和治疗策略得到了改善。德国心脏病学家的工作在心脏 EP 和导管消融领域取得了新的成就。在本文中，我们总结了德国 EP 中心在该领域的选择性贡献。

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1
From early beginnings to elaborate tools: contribution of German electrophysiology to the interventional treatment of cardiac arrhythmias : The German Cardiac Society welcomes ESC in Munich 2018.从早期的开端到精细的工具：德国电生理学对心律失常介入治疗的贡献：德国心脏学会欢迎 2018 年在慕尼黑举行的 ESC。
Clin Res Cardiol. 2018 Aug;107(Suppl 2):94-99. doi: 10.1007/s00392-018-1319-y. Epub 2018 Jul 13.
2
[Cardiac arrhythmias (VI). The radiofrequency ablation of accessory atrioventricular pathways].[心律失常（VI）。房室旁道的射频消融术]
Rev Esp Cardiol. 1993 Jun;46(6):367-80.
3
[Development of catheter ablation of supraventricular tachycardias with special consideration of contributions from German engineers and electrophysiologists].[室上性心动过速导管消融术的发展，特别考虑德国工程师和电生理学家的贡献]
Herzschrittmacherther Elektrophysiol. 2024 Mar;35(Suppl 1):110-117. doi: 10.1007/s00399-024-01009-x. Epub 2024 Feb 28.
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A young man with frequent episodes of palpitations.一名年轻男子，心悸频发。
Heart Rhythm. 2017 Sep;14(9):1419-1420. doi: 10.1016/j.hrthm.2017.04.037.
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Current role of catheter ablative procedures in patients with cardiac arrhythmias. A report for health professionals from the Subcommittee on Electrocardiography and Electrophysiology, American Heart Association.导管消融术在心律失常患者中的当前作用。美国心脏协会心电图与电生理小组委员会给卫生专业人员的报告。
Circulation. 1991 Jun;83(6):2146-53. doi: 10.1161/01.cir.83.6.2146.
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Cardiac electrophysiology studies and ablations for treatment of supraventricular arrhythmias--an initial experience from Karachi.用于治疗室上性心律失常的心脏电生理研究与消融术——来自卡拉奇的初步经验
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[Radiofrequency transcatheter ablation of anomalous left atrioventricular pathways: the role of the transseptal approach].[经导管射频消融治疗左侧房室旁路：经房间隔途径的作用]
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Isr Med Assoc J. 2007 Apr;9(4):260-4.

引用本文的文献

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German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management.德国心脏病学会细胞电生理学工作组最新论文：分子机制对临床心律失常管理的影响。
Clin Res Cardiol. 2019 Jun;108(6):577-599. doi: 10.1007/s00392-018-1377-1. Epub 2018 Oct 10.

本文引用的文献

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Manual Versus Robotic Catheter Ablation for the Treatment of Atrial Fibrillation: The Man and Machine Trial.《经导管手动消融术与机器人消融术治疗心房颤动的比较：Man and Machine 试验》。
JACC Clin Electrophysiol. 2017 Aug;3(8):875-883. doi: 10.1016/j.jacep.2017.01.024. Epub 2017 Jun 28.
2
Ten-Year Clinical Outcome After Circumferential Pulmonary Vein Isolation Utilizing the Hamburg Approach in Patients With Symptomatic Drug-Refractory Paroxysmal Atrial Fibrillation.利用汉堡方法行环肺静脉电隔离术治疗症状性药物难治性阵发性心房颤动的十年临床转归。
Circ Arrhythm Electrophysiol. 2018 Feb;11(2):e005250. doi: 10.1161/CIRCEP.117.005250.
3
Catheter Ablation for Atrial Fibrillation with Heart Failure.
心力衰竭合并心房颤动的导管消融治疗。
N Engl J Med. 2018 Feb 1;378(5):417-427. doi: 10.1056/NEJMoa1707855.
4
Laser Balloon or Wide-Area Circumferential Irrigated Radiofrequency Ablation for Persistent Atrial Fibrillation: A Multicenter Prospective Randomized Study.激光球囊或大面积环周灌注射频消融治疗持续性心房颤动：一项多中心前瞻性随机研究。
Circ Arrhythm Electrophysiol. 2017 Dec;10(12). doi: 10.1161/CIRCEP.117.005767.
5
Impact of Substrate Modification by Catheter Ablation on Implantable Cardioverter-Defibrillator Interventions in Patients With Unstable Ventricular Arrhythmias and Coronary Artery Disease: Results From the Multicenter Randomized Controlled SMS (Substrate Modification Study).导管消融进行基质改良对不稳定室性心律失常和冠状动脉疾病患者植入式心律转复除颤器干预的影响：多中心随机对照SMS（基质改良研究）结果
Circ Arrhythm Electrophysiol. 2017 Mar;10(3). doi: 10.1161/CIRCEP.116.004422.
6
First insights into cryoballoon-based pulmonary vein isolation taking the individual time-to-isolation into account.考虑到隔离所需的个体时间，对基于冷冻球囊的肺静脉隔离的初步观察。
Europace. 2017 Oct 1;19(10):1676-1680. doi: 10.1093/europace/euw233.
7
Individualized cryoballoon energy pulmonary vein isolation guided by real-time pulmonary vein recordings, the randomized ICE-T trial.实时肺静脉记录引导下的个体化冷冻球囊能量肺静脉隔离，随机ICE-T试验。
Heart Rhythm. 2017 Apr;14(4):495-500. doi: 10.1016/j.hrthm.2016.12.014. Epub 2016 Dec 9.
8
Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure.非缺血性收缩性心力衰竭患者的除颤器植入
N Engl J Med. 2016 Sep 29;375(13):1221-30. doi: 10.1056/NEJMoa1608029. Epub 2016 Aug 27.
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Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation.冷冻球囊或射频消融治疗阵发性心房颤动。
N Engl J Med. 2016 Jun 9;374(23):2235-45. doi: 10.1056/NEJMoa1602014. Epub 2016 Apr 4.
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Impact of Complete Versus Incomplete Circumferential Lines Around the Pulmonary Veins During Catheter Ablation of Paroxysmal Atrial Fibrillation: Results From the Gap-Atrial Fibrillation-German Atrial Fibrillation Competence Network 1 Trial.肺静脉周围完全环与不完全环在阵发性心房颤动导管消融中的影响：来自间隙性心房颤动-德国心房颤动能力网络 1 试验的结果。
Circ Arrhythm Electrophysiol. 2016 Jan;9(1):e003337. doi: 10.1161/CIRCEP.115.003337.