Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile.
作者信息
Solomon David A, Korshunov Andrey, Sill Martin, Jones David T W, Kool Marcel, Pfister Stefan M, Fan Xuemo, Bannykh Serguei, Hu Jethro, Danielpour Moise, Li Rong, Johnston James, Cham Elaine, Cooney Tabitha, Sun Peter P, Oberheim Bush Nancy Ann, McDermott Michael, Van Ziffle Jessica, Onodera Courtney, Grenert James P, Bastian Boris C, Villanueva-Meyer Javier E, Pekmezci Melike, Bollen Andrew W, Perry Arie
机构信息
Department of Pathology, University of California, San Francisco, CA, USA.
Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
出版信息
Acta Neuropathol. 2018 Aug;136(2):339-343. doi: 10.1007/s00401-018-1883-2. Epub 2018 Jul 13.
Abstract
摘要
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Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile.透明隔和侧脑室黏液样神经胶质神经元肿瘤由复发性血小板衍生生长因子受体A（PDGFRA）p.K385突变和类似弥漫性星形细胞瘤伴少突胶质细胞成分（DNT）的甲基化谱所定义。
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