Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
Department of Obstetrics and Gynecology, CHA Seoul Fertility Center, CHA University, 416 Hangangdaero, Joongku, Seoul, Republic of Korea.
J Assist Reprod Genet. 2018 Sep;35(9):1623-1630. doi: 10.1007/s10815-018-1255-9. Epub 2018 Jul 13.
The aim of this study is to analyze women's opinions and their decision making processes regarding elective oocyte cryopreservation (OC).
One hundred twenty-four women who had elective OC counseling at the CHA Seoul Fertility Center were asked to complete a survey after their first visit. Data collection regarding age, marital status, monthly income, occupation, religion, reproductive history, questions about the participant's view on their own fecundity, and future parenthood were included. The modified Reproductive Concerns After Cancer scale and the Decisional Conflict Scale were used for analysis.
The participants' mean age was 37.1 ± 4.8 years old. Eighty-six percent of the participants had regular periods. Ninety-two percent thought it was important to have their own biological offspring, and 86% were willing to pursue OC. Forty-nine percent appeared to have high DCS scores regarding making a decision of OC. Sixty-eight percent pursued OC, and the mean number of oocytes cryopreserved per patient was 10.5 ± 8.3. Multivariate analysis revealed that age was the only factor associated with high DCS scores (P = 0.002). Feeling less fertile than other women of same age and low DCS scores were the factors associated with pursuing OC (P = 0.02 and 0.004, respectively) after adjusting for possible confounding factors, including age.
Older women had more difficulties in making decisions about OC. Adjusting for age, women who thought that they were less fertile than other women of same age and those with lower decisional conflict were more likely to pursue OC. Further studies should focus on the validation of older women's decisional conflicts regarding OC.
本研究旨在分析女性对选择性卵母细胞冷冻(OC)的意见及其决策过程。
对在 CHA 首尔生育中心接受选择性 OC 咨询的 124 名女性进行调查,要求她们在首次就诊后完成一份调查。数据收集包括年龄、婚姻状况、月收入、职业、宗教、生育史、关于参与者对自身生育能力看法的问题以及未来的育儿计划。使用改良后的癌症后生殖关注量表和决策冲突量表进行分析。
参与者的平均年龄为 37.1±4.8 岁。86%的参与者月经规律。92%的参与者认为拥有自己的亲生子女很重要,86%的参与者愿意进行 OC。49%的参与者在进行 OC 决策时似乎存在较高的 DCS 评分。68%的参与者进行了 OC,每位患者平均冷冻了 10.5±8.3 个卵母细胞。多变量分析显示,年龄是唯一与高 DCS 评分相关的因素(P=0.002)。与同龄女性相比感觉自己生育能力较低以及 DCS 评分较低是进行 OC 的相关因素(调整可能的混杂因素后,P=0.02 和 0.004)。
年龄较大的女性在进行 OC 决策时面临更多困难。在调整年龄因素后,那些认为自己比同龄女性生育能力较低以及决策冲突较小的女性更有可能进行 OC。未来的研究应侧重于验证老年女性对 OC 的决策冲突。