Melbourne Dental School, University of Melbourne, Carlton, Victoria, Australia.
Centre for Medicine Use and Safety, Monash University, Parkville, Victoria, Australia.
Aust Dent J. 2018 Dec;63(4):414-421. doi: 10.1111/adj.12643. Epub 2018 Aug 2.
Antibiotic resistance is a well-established global public health crisis, with the use and misuse of antibiotics being the principal cause of bacterial resistance. Studies in both Australia and overseas have demonstrated that the dental prescribing of antibiotics is increasing and that dentists tend to prescribe antibiotics unnecessarily and for incorrect clinical indications. Dental practitioners in Australia also prefer to prescribe moderate to broad-spectrum antibacterial agents and make some inappropriate antibiotic prescribing choices. This review aims to inform dentists about the overall scope and development of bacterial resistance, approaches and challenges to reducing resistance and, ultimately, the role of dental prescribers in practising with optimal antibiotic stewardship.
抗生素耐药性是一个既定的全球公共卫生危机，抗生素的使用和滥用是细菌耐药性的主要原因。澳大利亚和海外的研究表明，牙医开具抗生素的情况正在增加，而且牙医往往不必要地开具抗生素，并且开具的临床指征不正确。澳大利亚的牙科医生也更愿意开中等至广谱抗菌药物，并做出一些不适当的抗生素处方选择。本综述旨在让牙医了解细菌耐药性的总体范围和发展，减少耐药性的方法和挑战，以及牙科医生在最佳抗生素管理实践中的作用。
