Royal Hallamshire Hospital, Sheffield, UK.
Royal Hallamshire Hospital, Sheffield, UK.
Eur Urol Focus. 2019 Sep;5(5):894-898. doi: 10.1016/j.euf.2018.06.013. Epub 2018 Jul 11.
Penile paraffinoma is a rare cause of penile mass that can occur following injection of liquid paraffin, performed illicitly for penile augmentation. Over the past 2 yr, we have observed an increasing number of cases presenting with the complications of penile paraffinoma; three patients of central European origin have required inpatient treatment at our institution and posed a significant management dilemma. This mini-review aims to review the literature on the aetiopathogenesis, clinical features, diagnosis, and management of penile paraffinoma. A systematic search of PubMed and Scopus was performed with 10 case series and 26 case reports identified between 1956 and 2017. A total of 124 cases, with a mean age of 36.29 yr, were identified. The majority originated in Korea, and the most common injected material was liquid paraffin (80.6%). Patients presented with pain/swelling, ulceration/fistulae, and penile deformity. The majority required surgical excision of paraffinoma followed by reconstruction with a variety of procedures including split skin grafting, scrotal skin flap reconstruction, and prepuce grafting. Mean duration of follow-up was 15.8 mo. Penile paraffinoma remains a rare presentation; however, it can present management difficulties. We have had an increase in cases, with three patients presenting with complications following injection of paraffin in our unit in the past 2 yr. Definitive management includes surgical excision and reconstruction as required with early involvement of plastic surgeons. There may be a role for conservative management; however, long-term outcomes are unclear. There may be a need for targeted preventative measures through public health agencies in communities where the practice is more prevalent. PATIENT SUMMARY: Penile paraffinoma can occur following injection of liquid paraffin or similar substances, generally used by non-healthcare personnel for the purpose of penile augmentations, and can cause significant pain, ulceration, and penile deformity. Definitive management includes surgical excision with reconstruction as required. Prevention of its use through awareness and education may be required in communities where the practice is more common.
阴茎石蜡瘤是一种罕见的阴茎肿块原因,可发生在注射液体石蜡后,非法用于阴茎增大。在过去的 2 年中,我们观察到越来越多的病例出现阴茎石蜡瘤并发症;有 3 名中欧血统的患者在我们机构接受住院治疗,这给治疗带来了很大的困难。本篇小型综述旨在回顾阴茎石蜡瘤的病因、发病机制、临床特征、诊断和治疗的文献。我们对 1956 年至 2017 年期间的 PubMed 和 Scopus 进行了系统检索,共确定了 10 个病例系列和 26 个病例报告,共 124 例,平均年龄为 36.29 岁。大多数病例来自韩国,最常见的注射材料是液体石蜡(80.6%)。患者表现为疼痛/肿胀、溃疡/瘘管和阴茎畸形。大多数患者需要手术切除石蜡瘤,然后采用多种方法进行重建,包括皮肤移植、阴囊皮瓣重建和包皮移植。平均随访时间为 15.8 个月。阴茎石蜡瘤仍然是一种罕见的表现,但它可能会带来治疗上的困难。在过去的 2 年中,我们单位有 3 例患者在注射石蜡后出现并发症,因此我们遇到的病例有所增加。明确的治疗方法包括必要时手术切除和重建,并尽早请整形外科医生参与。可能需要保守治疗,但长期结果尚不清楚。在注射石蜡瘤更为常见的社区,可能需要通过公共卫生机构采取有针对性的预防措施。患者总结:阴茎石蜡瘤可在注射液体石蜡或类似物质后发生,通常由非医务人员用于阴茎增大,可导致严重疼痛、溃疡和阴茎畸形。明确的治疗方法包括必要时手术切除和重建。在注射石蜡瘤更为常见的社区,可能需要通过提高认识和教育来预防其使用。