LAQV/REQUIMTE, Faculty of Pharmacy, University of Porto, Porto, Portugal.
LAQV/REQUIMTE, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Food Res Int. 2018 Sep;111:724-731. doi: 10.1016/j.foodres.2018.06.012. Epub 2018 Jun 5.
The nutritional composition of Calluna vulgaris flowers as well as the phytochemical profile, antioxidant (DPPH and FRAP assays), antimicrobial and cytotoxic (in human immortalized non-tumorigenic keratinocyte and fibroblasts) activities of aqueous, hydroalcoholic and ethanolic extracts were evaluated. A high content of fiber and carbohydrates (75%) and the prevalence of α-tocopherol as vitamer deserves attention. Linolenic (35%), linoleic (27%) and palmitic (21%) acids were the most abundant fatty acids. Qualitative and quantitative analysis by LC-MS and NMR indicated high levels of quercetin, kaempferol and myricetin derivatives as well as procyanidins. The hydro-alcoholic extract displayed the highest antioxidant activity and total phenolics (TPC) and flavonoid contents (TFC). No adverse effects on cells were observed until a concentration of 100 μg/mL and a good antimicrobial activity was reported against S. epidermidis and S. aureus with the hydro-alcoholic extract. The data obtained demonstrated that wild plants like heather, although not being a common nutritional reference, can be used in an alimentary base as a source of bioactive compounds, namely antioxidants.
我们评估了普通金雀花花朵的营养成分以及植物化学成分、抗氧化（DPPH 和 FRAP 测定法）、抗菌（在人永生化非肿瘤性角质形成细胞和成纤维细胞中）和细胞毒性（在人永生化非肿瘤性角质形成细胞和成纤维细胞中）活性。其富含纤维和碳水化合物（75%），以 α-生育酚作为维生素 E 的前体为主值得关注。亚麻酸（35%）、亚油酸（27%）和棕榈酸（21%）是最丰富的脂肪酸。通过 LC-MS 和 NMR 进行的定性和定量分析表明，槲皮素、山柰酚和杨梅素衍生物以及原花青素的含量很高。水醇提取物显示出最高的抗氧化活性和总酚（TPC）和类黄酮含量（TFC）。在 100μg/mL 浓度下，对细胞没有观察到不良反应，并报道水醇提取物对表皮葡萄球菌和金黄色葡萄球菌具有良好的抗菌活性。所获得的数据表明，野生植物，如石楠，虽然不是常见的营养参考，但可以用作饮食基础的生物活性化合物来源，即抗氧化剂。
