López-Sanromán Antonio, Clofent Joan, Garcia-Planella Esther, Menchén Luis, Nos Pilar, Rodríguez-Lago Iago, Domènech Eugeni
Servicio de Gastroenterología y Hepatología, Hospital Ramón y Cajal, Madrid, España.
Servicio de Aparato Digestivo, Hospital de Sagunto, Sagunto, Valencia, España.
Gastroenterol Hepatol. 2018 Aug-Sep;41(7):458-471. doi: 10.1016/j.gastrohep.2018.05.013. Epub 2018 Jul 12.
Oral budesonide is a glucocorticoid of primarily local action. In the field of digestive diseases, it is used mainly in inflammatory bowel disease, but also in other indications. This review addresses the pharmacology, pharmacodynamics and therapeutic use of budesonide. Its approved indications are reviewed, as well as other clinical scenarios in which it could play a role, in order to facilitate its use and improve the accuracy of its prescription.
口服布地奈德是一种主要具有局部作用的糖皮质激素。在消化系统疾病领域,它主要用于炎症性肠病,但也用于其他适应症。本文综述了布地奈德的药理学、药效学及治疗用途。对其已批准的适应症以及其他可能发挥作用的临床情况进行了综述,以促进其使用并提高处方的准确性。