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回顾布地奈德在克罗恩病中的治疗作用。

Reviewing the therapeutic role of budesonide in Crohn's disease.

作者信息

López-Sanromán Antonio, Clofent Joan, Garcia-Planella Esther, Menchén Luis, Nos Pilar, Rodríguez-Lago Iago, Domènech Eugeni

机构信息

Servicio de Gastroenterología y Hepatología, Hospital Ramón y Cajal, Madrid, España.

Servicio de Aparato Digestivo, Hospital de Sagunto, Sagunto, Valencia, España.

出版信息

Gastroenterol Hepatol. 2018 Aug-Sep;41(7):458-471. doi: 10.1016/j.gastrohep.2018.05.013. Epub 2018 Jul 12.

DOI:10.1016/j.gastrohep.2018.05.013
PMID:30007787
Abstract

Oral budesonide is a glucocorticoid of primarily local action. In the field of digestive diseases, it is used mainly in inflammatory bowel disease, but also in other indications. This review addresses the pharmacology, pharmacodynamics and therapeutic use of budesonide. Its approved indications are reviewed, as well as other clinical scenarios in which it could play a role, in order to facilitate its use and improve the accuracy of its prescription.

摘要

口服布地奈德是一种主要具有局部作用的糖皮质激素。在消化系统疾病领域,它主要用于炎症性肠病,但也用于其他适应症。本文综述了布地奈德的药理学、药效学及治疗用途。对其已批准的适应症以及其他可能发挥作用的临床情况进行了综述,以促进其使用并提高处方的准确性。

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1
Reviewing the therapeutic role of budesonide in Crohn's disease.回顾布地奈德在克罗恩病中的治疗作用。
Gastroenterol Hepatol. 2018 Aug-Sep;41(7):458-471. doi: 10.1016/j.gastrohep.2018.05.013. Epub 2018 Jul 12.
2
Budesonide for Crohn's disease.布地奈德用于克罗恩病
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Low-dose budesonide treatment for prevention of postoperative recurrence of Crohn's disease: a multicentre randomized placebo-controlled trial. German Budesonide Study Group.低剂量布地奈德治疗预防克罗恩病术后复发:一项多中心随机安慰剂对照试验。德国布地奈德研究组
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Oral budesonide for induction of remission in ulcerative colitis.口服布地奈德诱导溃疡性结肠炎缓解
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Review article: Targeted drug delivery in treatment of intestinal diseases.综述文章:肠道疾病治疗中的靶向药物递送
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