Assan R, Alexandre J H, Tiengo A, Marre M, Costamailleres L, Lhomme C
Diabete Metab. 1985 Oct;11(5):303-9.
Thirty-six totally depancreatectomized patients were followed up for 4-124 months. Pancreatectomy had been performed because of fulminant pancreatitis (in 10), chronic hyperalgic otherwise untractable pancreatitis (in 7), exocrine carcinoma of the pancreas (in 16), cystadenocarcinoma of the pancreas (in 2) and insulinoma (in 1). The longest survival duration was in chronic pancreatitis patients: 57 +/- 17 months. A normal socio-professional reinsertion was obtained in 16 patients, mainly those with non-malignant pancreotopathies. At the end of the survey, ten of the carcinoma patients had died, versus none in the other groups. Diabetes mellitus was characterized by the absence of ketonuria, and the frequent occurrence of hypoglycemia (in 15 patients) and infection (in 6). Malabsorption caused osteomalacia in one patient.
36例全胰切除患者接受了4至124个月的随访。行胰切除术的原因包括暴发性胰腺炎（10例）、慢性疼痛性难治性胰腺炎（7例）、胰腺外分泌癌（16例）、胰腺囊腺癌（2例）和胰岛素瘤（1例）。生存时间最长的是慢性胰腺炎患者：57±17个月。16例患者实现了正常的社会职业再融入，主要是那些患有非恶性胰腺疾病的患者。调查结束时，10例癌症患者死亡，其他组无一例死亡。糖尿病的特点是无酮尿症，频繁发生低血糖（15例患者）和感染（6例）。吸收不良导致1例患者出现骨软化症。
