Hussain Sana, Hasnain Jamshed, Hussain Zareen, Badshah Masroor, Siddique Hafeez, Fiske Christina, Pettit April
Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology, (SZABIST), Karachi, Pakistan.
Bridge Consultants Foundation, Karachi, Pakistan.
Open Infect Dis J. 2018;10:37-42. doi: 10.2174/1874279301810010037. Epub 2018 May 18.
The World Health Organization has recommended a patient-centered approach to tuberculosis drug administration. A central element of the patient-centered strategy is the use of treatment supporters to evaluate and elevate adherence to the treatment regimen and to address poor adherence when it occurs. This study was led to determine the part of various treatment supporters in the successful completion of treatment.
This study was conducted in two locales of Sindh, Hyderabad and Mirpurkhas. Information gathered included age, gender, regions, sort of treatment supporters (relatives, community and health facility workers) and treatment outcomes.
Of the 773 patients incorporated into the study, 86.8% picked a family supporter, 7.63% selected community worker and 5.56% chose health facility worker as their treatment supporter. Women and younger patients were more likely to prefer that family members supervise their treatment. Treatment achievement rates among the patients regulated by the three kinds of treatment supporters, were not altogether unique in relation to each other (=0.23 Chi square).
The study demonstrates that TB patients ought to be urged to pick the supporter of their inclination as selection of treatment supporter outside the health system does not adversely affect TB treatment outcomes in limited resource settings.
世界卫生组织推荐采用以患者为中心的方法进行结核病药物管理。以患者为中心策略的一个核心要素是利用治疗支持者来评估和提高对治疗方案的依从性，并在出现依从性差的情况时加以解决。开展这项研究是为了确定各类治疗支持者在治疗成功完成过程中所起的作用。
本研究在信德省的两个地区——海得拉巴和米尔布尔哈斯进行。收集的信息包括年龄、性别、地区、治疗支持者类型（亲属、社区和卫生机构工作人员）以及治疗结果。
纳入该研究的773名患者中，86.8%选择家庭支持者，7.63%选择社区工作者，5.56%选择卫生机构工作人员作为他们的治疗支持者。女性和年轻患者更倾向于让家庭成员监督他们的治疗。由这三种治疗支持者管理的患者的治疗成功率彼此之间并无显著差异（卡方值=0.23）。
该研究表明，应鼓励结核病患者选择他们倾向的支持者，因为在资源有限的环境中，选择卫生系统之外的治疗支持者不会对结核病治疗结果产生不利影响。
