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青春期每天连续暴露于 900MHz 电磁场内 1 小时对 60 日龄 Sprague Dawley 大鼠睾丸形态和氧化应激生物标志物的影响。

Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence.

机构信息

Department of Histology and Embryology, Karadeniz Technical University, Faculty of Medicine, TR-61080 Trabzon, Turkey.

Department of Histology and Embryology, Karadeniz Technical University, Faculty of Medicine, TR-61080 Trabzon, Turkey.

出版信息

Reprod Toxicol. 2018 Oct;81:71-78. doi: 10.1016/j.reprotox.2018.07.002. Epub 2018 Jul 23.

Abstract

The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and biochemical analysis methods. Twenty-four Sprague Dawley rats aged 21 days were randomly and equally (n = 8) divided into three groups. No procedure was performed on the control group rats. The sham group rats were held in an EMF-cage without exposure to EMF. The EMF group rats were exposed to continuous 900-MHz EMF for 1 h each day inside the EMF-cage during adolescence. On postnatal day 60 the testes were extracted and divided into right and left halves. The right half was used for histopathological evaluation and the left half for biochemical analyses. Our results show that changes may occur in morphology and oxidative stress biomarkers in the rat testis following exposure to continuous 900-MHz EMF throughout the adolescent period.

摘要

本研究旨在通过组织病理学和生化分析方法,研究连续 900MHz 电磁辐射(EMF)暴露对青春期雄性大鼠睾丸的影响。将 24 只 21 天大的 Sprague Dawley 大鼠随机平均分为三组(n=8)。对照组大鼠不进行任何处理。假辐射组大鼠置于 EMF 笼中但不接受 EMF 辐射。辐射组大鼠在青春期每天 1 小时置于 EMF 笼中接受连续 900MHz EMF 辐射。在出生后第 60 天,提取睾丸并分为左右两半。右半部分用于组织病理学评估,左半部分用于生化分析。我们的结果表明,连续 900MHz EMF 暴露可能导致青春期雄性大鼠睾丸形态和氧化应激生物标志物发生变化。

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