Zenoble R D, Kemppainen R J, Young D W, Carpenter J W
J Am Vet Med Assoc. 1985 Dec 1;187(11):1119-20.
The effect of ACTH on plasma corticosterone and cortisol was determined in 12 eagles (Haliaeetus leucocephalus) and in 6 Andean condors (Vultur gryphus). In all raptors, the concentration of plasma corticosterone was substantially greater than that of cortisol. After ACTH administration, the eagles had a marked increase (P less than 0.001) in plasma corticosterone concentrations, but not in plasma cortisol. Administration of saline solution did not induce increased plasma corticosterone concentrations in the eagles. The condors had a smaller increase (P less than 0.002) in plasma corticosterone concentrations after ACTH administration, as compared with that of the eagles. However, administration of saline solution in 2 condors resulted in an increase in corticosterone similar to the increase after ACTH administration. In the condor, a stress-related release of endogenous ACTH may have an effect similar to that induced by exogenously administered ACTH. Plasma cortisol concentrations did not increase significantly after administration of ACTH or saline solution in either raptor species.
在12只白头海雕(Haliaeetus leucocephalus)和6只安第斯神鹫(Vultur gryphus)中测定了促肾上腺皮质激素(ACTH)对血浆皮质酮和皮质醇的影响。在所有猛禽中,血浆皮质酮的浓度显著高于皮质醇。给予ACTH后,白头海雕血浆皮质酮浓度显著升高(P<0.001),但血浆皮质醇浓度未升高。给予生理盐水未引起白头海雕血浆皮质酮浓度升高。与白头海雕相比,安第斯神鹫给予ACTH后血浆皮质酮浓度升高幅度较小(P<0.002)。然而,2只安第斯神鹫给予生理盐水后,皮质酮升高幅度与给予ACTH后相似。在安第斯神鹫中,内源性ACTH的应激相关释放可能具有与外源性给予ACTH相似的作用。两种猛禽给予ACTH或生理盐水后,血浆皮质醇浓度均未显著升高。