Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156 Oeiras, Portugal.
Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156 Oeiras, Portugal.
Curr Opin Cell Biol. 2018 Dec;55:81-86. doi: 10.1016/j.ceb.2018.05.009. Epub 2018 Jul 14.
The large display of body shapes and sizes observed among vertebrates ultimately represent variations of a common basic body plan. This likely results from the use of homologous developmental schemes, just differentially tinkered both in amplitude and timing by natural selection. In this review, we will revisit, discuss and combine old ideas with new concepts to update our view on how the vertebrate body is built. Recent advances, particularly at the molecular level, will guide our deconstruction of the individual developmental modules that sequentially produce head, neck, trunk and tail structures, and the transitions between them.
在脊椎动物中观察到的体型和大小的大量表现最终代表了共同基本身体计划的变化。这可能是由于同源发育方案的使用，只是自然选择在幅度和时间上有所不同。在这篇综述中，我们将重新审视、讨论和结合旧的概念和新的概念，以更新我们对脊椎动物身体结构的看法。最近的进展，特别是在分子水平上，将指导我们对依次产生头部、颈部、躯干和尾部结构以及它们之间的过渡的个体发育模块进行解构。
