Champault G, Patel J C, Pourriat J L, Garnier M, Fabre F, Psalmon F
Nouv Presse Med. 1977 Feb 12;6(6):435-8.
The authors carried out high flow intestinal lavage during gastrointestinal bleeding in cirrhotics in order to obtain rapid elimination of blood from the intestine and thereby reduce the risk of encephalopathy. The fluid used had been developed for preparation of the colon for surgery and was responsible for water and electrolyte disturbances with water and salt retention. Without criticising the principle of lavage in the prevention of encephalopathy, the authors express certain reserves with regard to the use of this solution and suggest the use of a sodium-free substance remaining within the intestinal lumen (hypertonic mannitol) which does not cause any water/electrolyte imbalance, is more effective and would appear to have a slight though definite action on the resorption of ascites.
作者们对肝硬化患者胃肠道出血时进行了高流量肠道灌洗，目的是迅速清除肠道内的血液，从而降低肝性脑病的风险。所使用的灌洗液是为结肠手术准备而研制的，会导致水和电解质紊乱以及水盐潴留。在不批评灌洗预防肝性脑病这一原则的情况下，作者们对该溶液的使用表示了一定的保留意见，并建议使用一种留在肠腔内的无钠物质（高渗甘露醇），它不会引起任何水/电解质失衡，更有效，而且似乎对腹水吸收有轻微但明确的作用。
