Fudge T L, Ochsner J L, Mills N L
South Med J. 1977 Jan;70(1):29-32. doi: 10.1097/00007611-197701000-00015.
Fifty-eight patients had surgical treatment of postinfarction ventricular aneurysm. Resection was performed in 47 patients and plication in 11. There were 44 combined procedures, mostly myocardial revascularizations. Indications for operation included congestive heart failure, angina, arrhythmias, and thromboembolic phenomena. All aneurysms were documented by cineventriculography, and 54 patients had coronary cineangiograms. Left ventricular end diastolic (LVED) pressures ranged from 25 to 50 in 25 of the patients but did not affect mortality. Hospital mortality (14% overall) was directly proportional to degree of coronary artery disease--single vessel, 0; double vessel, 10%; triple, 24%. Nine patients are alive more than six months postoperatively and 37 are alive from six months to eight years postoperatively. We conclude that aneurysmectomy is the procedure of choice for ventricular aneurysms that are hemodynamically significant or have produced ventricular clots, arrhythmias, or embolic phenomena. An LVED of greater than 25 mm Hg does not contraindicate operation, but triple vessel coronary disease increases the risk.
58例患者接受了心肌梗死后室壁瘤的手术治疗。47例行切除术,11例行折叠术。有44例联合手术,多数为心肌血运重建术。手术指征包括充血性心力衰竭、心绞痛、心律失常和血栓栓塞现象。所有室壁瘤均经心血管造影记录,54例患者进行了冠状动脉造影。25例患者的左心室舒张末期(LVED)压力在25至50之间,但不影响死亡率。医院死亡率(总体为14%)与冠状动脉疾病程度直接相关——单支血管病变为0;双支血管病变为10%;三支血管病变为24%。9例患者术后存活超过6个月,37例患者术后存活6个月至8年。我们得出结论,对于具有血流动力学意义或已产生心室血栓、心律失常或栓塞现象的室壁瘤,动脉瘤切除术是首选手术方式。LVED大于25 mmHg并非手术禁忌,但三支血管冠状动脉疾病会增加手术风险。