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结膜囊内的细菌生长与眼球外部的局部防御

Bacterial growth in the conjunctival sac and the local defense of the outer eye.

作者信息

Jensen O L, Gluud B S

出版信息

Acta Ophthalmol Suppl (1985). 1985;173:80-2. doi: 10.1111/j.1755-3768.1985.tb06849.x.

DOI:10.1111/j.1755-3768.1985.tb06849.x
PMID:3002113
Abstract

25 patients admitted for cataract surgery were subjected to conjunctival bacterial culturings preoperatively and during the postoperative observation period. Simultaneously lactoferrin (LF), lysozyme (LY) and secretory immunoglobulin A (s-IgA) were measured in tears. The preoperative flora disclosed the growth of Staphylococcus albus (SA) and diphtheroids. Other species were only sporadically present. There was a significant rise in number of patients affected by SA and diphtheroids postoperatively (from 60 to 80%), whereas other bacteria were not present to any significant extent. LF, LY and s-IgA concentration decreased to about 50% of the preoperative level in the early postoperative period gradually returning towards their initial concentration. Correlating an antibacterial score with bacterial score we found a significant inverse relationship between the two (P less than 0.05).

摘要

25名因白内障手术入院的患者在术前及术后观察期均进行了结膜细菌培养。同时,检测了泪液中的乳铁蛋白(LF)、溶菌酶(LY)和分泌型免疫球蛋白A(s-IgA)。术前菌群显示有白色葡萄球菌(SA)和类白喉杆菌生长。其他菌种仅偶尔出现。术后受SA和类白喉杆菌影响的患者数量显著增加(从60%增至80%),而其他细菌则未大量出现。术后早期,LF、LY和s-IgA浓度降至术前水平的约50%,随后逐渐恢复至初始浓度。将抗菌评分与细菌评分相关联,我们发现两者之间存在显著的负相关(P<0.05)。

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