Sand B B, Jensen O L, Eriksen J S, Vinding T
Acta Ophthalmol (Copenh). 1986 Oct;64(5):504-8. doi: 10.1111/j.1755-3768.1986.tb06962.x.
Lysozyme (ly) concentration in tears was measured the day before and the days following intracapsular cataract extraction in 25 patients. A median ly concentration of 1.30 mg/ml was found pre-operatively. On the first post-operative day a significant drop in the median ly concentration was observed (0.58 mg/ml). Thereafter a gradual rise towards pre-operative level was found at the 12th post-operative day. An inverse correlation existed between ly concentrations and Schirmer values during the observation period, and dilution thus seems to be an important cause of the post-operative drop in ly concentration. We observed an inverse relationship between ly level, and the number (%) of patients displaying bacterial colonization of the conjunctival sac 24 h later. The most frequently isolated bacteria were staphylococcus albus and diphteroids. It is proposed that the drop in ly concentration post-operatively may contribute to an increased risk of bacterial colonization of the eye post-operatively.
对25例患者在白内障囊内摘除术前一天及术后数天测量泪液中溶菌酶（ly）浓度。术前溶菌酶浓度中位数为1.30mg/ml。术后第一天，溶菌酶浓度中位数显著下降（0.58mg/ml）。此后，在术后第12天发现其逐渐上升至术前水平。观察期内溶菌酶浓度与泪液分泌试验值呈负相关，因此稀释似乎是术后溶菌酶浓度下降的一个重要原因。我们观察到溶菌酶水平与24小时后结膜囊出现细菌定植的患者数量（%）之间呈负相关。最常分离出的细菌是白色葡萄球菌和类白喉杆菌。有人提出，术后溶菌酶浓度下降可能会增加术后眼部细菌定植的风险。
