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与脉络膜痣相关的息肉样病变:厚脉络膜疾病谱?

Polypoidal lesions associated to choroidal naevus: spectrum of pachychoroid disease?

作者信息

Anzidei Rossella, De La Mata Guillermo, Deane James

机构信息

Department of Ophthalmology, Leicester Royal Infirmary, Leicester, UK.

出版信息

BMJ Case Rep. 2018 Jul 18;2018:bcr-2018-225571. doi: 10.1136/bcr-2018-225571.

Abstract

A 78-year-old woman was referred by an optician for an incidental finding of peripapillary naevus in the absence of visual symptoms. On examination, the right eye showed a choroidal naevus of around 1.5 disc diameter, adjacent to the optic disc. Optical coherence tomography detected the presence of pigment epithelium detachment and subretinal fluid within the context of the naevus. Fundus fluorescein angiography and indocyanine green showed multiple polypoidal lesions (Polypoidal Choroidal Vasculopathy, PCV) in the choroid within the spectrum of a pachychoroid, without any sign of malignancy related to neovascularisation. The patient underwent a follow-up of 6 months, showing stability of the lesions over this timeframe. No treatment has been required since the polypoidal lesions were outside the fovea and visual acuity remained stable. The association between choroidal naevi and polypoidal lesions is rare; however, this seems to confirm that these findings are part of the spectrum of pachychoroid disease.

摘要

一名78岁女性因验光师偶然发现视乳头周围痣而前来就诊,她没有视觉症状。检查时,右眼显示一个约1.5视盘直径大小的脉络膜痣,紧邻视盘。光学相干断层扫描在痣的范围内检测到色素上皮脱离和视网膜下液。眼底荧光血管造影和吲哚菁绿显示在厚脉络膜范围内脉络膜有多个息肉样病变(息肉样脉络膜血管病变,PCV),没有任何与新生血管相关的恶性迹象。患者接受了6个月的随访,在此期间病变保持稳定。由于息肉样病变位于黄斑中心凹以外且视力保持稳定,因此无需治疗。脉络膜痣与息肉样病变之间的关联很少见;然而,这似乎证实了这些发现是厚脉络膜疾病谱的一部分。

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本文引用的文献

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Int Ophthalmol. 2018 Oct;38(5):2239-2246. doi: 10.1007/s10792-017-0666-4. Epub 2017 Aug 1.
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Choroidal nevus in an eye with polypoidal choroidal vasculopathy.伴有息肉样脉络膜血管病变的眼中的脉络膜痣。
Case Rep Ophthalmol. 2014 Dec 13;5(3):463-7. doi: 10.1159/000370044. eCollection 2014 Sep-Dec.
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Swept-source optical coherence tomography features of choroidal nevi.脉络膜痣的扫频源光学相干断层扫描特征
Am J Ophthalmol. 2015 Jan;159(1):169-76.e1. doi: 10.1016/j.ajo.2014.10.011. Epub 2014 Oct 14.
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