Bilgici Birşen, Gun Seda, Avci Bahattin, Akar Ayşegül, K Engiz Begüm
a Department of Biochemistry , Ondokuz Mayıs University , Samsun , Turkey.
b Department of Pathology , Ondokuz Mayıs University , Samsun , Turkey.
Int J Radiat Biol. 2018 Nov;94(11):1054-1061. doi: 10.1080/09553002.2018.1503430. Epub 2018 Sep 27.
To investigate the inflammatory effect and testicular damage on rats exposed to low level of electromagnetic fields (EMF) at 2.45 GHz microwave radiation.
Twenty two Wistar rats were divided into two groups. Group 1 was the control group and not exposed to EMF. Group 2 was exposed to low level EMF (average E-field 3.68 ± 0.36 V/m, whole body average SAR, 0.0233 W/kg, in 10 g tissue) at 2.45 GHz for 1 hour/day for 30 consecutive days. At the end of the study, interleukin-6 (IL-6), interleukin-10 (IL-10), interleukin-32 (IL-32), C-reactive protein (CRP) were measured in rat serum and IL-6, IL-10, IL-32 were measured in rat testis tissue. Furthermore, testicular tissues were evaluated histopathologically in terms of spermatogenesis and coagulation necrosis.
Serum IL-6 and CRP levels were found to be significantly different in the study group compared to the control group (p < .05), but no significant difference was found in serum IL-10, IL-32 levels and testis tissue IL-6, IL-10, IL-32 levels compared to the control group (p > .05). On the other hand, histopathological evaluation of testicular tissue revealed a significant difference in necrosis and spermatogenesis when compared with the control group (p < .05).
It may be concluded that low level EMF at 2.45 GHz increases inflammation and testicular damage and negative impact on male reproductive system function.
研究2.45 GHz微波辐射下低水平电磁场(EMF)对大鼠的炎症影响及睾丸损伤。
将22只Wistar大鼠分为两组。第1组为对照组,不暴露于EMF。第2组暴露于2.45 GHz的低水平EMF(平均电场强度3.68 ± 0.36 V/m,全身平均比吸收率,0.0233 W/kg,在10 g组织中),每天1小时,连续30天。在研究结束时,检测大鼠血清中的白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、白细胞介素-32(IL-32)、C反应蛋白(CRP)以及大鼠睾丸组织中的IL-6、IL-10、IL-32。此外,从生精和凝固性坏死方面对睾丸组织进行组织病理学评估。
与对照组相比,研究组血清IL-6和CRP水平存在显著差异(p < .05),但血清IL-10、IL-32水平以及睾丸组织IL-6、IL-10、IL-32水平与对照组相比无显著差异(p > .05)。另一方面,睾丸组织的组织病理学评估显示,与对照组相比,坏死和生精存在显著差异(p < .05)。
可以得出结论,2.45 GHz的低水平EMF会增加炎症和睾丸损伤,并对男性生殖系统功能产生负面影响。