Department of Internal Medicine (I), Osaka Medical College, 2-7 Daigaku-machi, Takatsuki 569-8686, Japan.
National Agriculture and Food Research Organization, Agri-Food Business Innovation Center, 3-1-1 Kannondai, Tsukuba 305-8517, Japan.
Nutrients. 2018 Jul 19;10(7):924. doi: 10.3390/nu10070924.
(1) Background: Arteriosclerosis is associated with high levels of low-density lipoprotein (LDL) cholesterol. -methylated catechins in "Benifuuki" green tea are expected to reduce cholesterol levels, although there is limited research regarding this topic; (2) Methods: This trial evaluated 159 healthy volunteers who were randomized to receive ice cream containing a high-dose of "Benifuuki" extract including 676 mg of catechins (group H), a low-dose of "Benifuuki" extract including 322 mg of catechins (group L), or no "Benifuuki" extract (group C). Each group consumed ice cream (with or without extract) daily for 12 weeks, and their lipid-related parameters were compared; (3) Results: A significant reduction in the level of lectin-like oxidized LDL receptor-1 ligand containing ApoB (LAB) was detected in group H, compared to groups L and C. No significant differences between the three groups were detected in their levels of total cholesterol, triglycerides, and LDL cholesterol; (4) Conclusions: "Benifuuki" extract containing -methylated catechins may help prevent arteriosclerosis.
(1)背景:动脉粥样硬化与低密度脂蛋白(LDL)胆固醇水平升高有关。“弁财天”绿茶中的 -甲基化儿茶素有望降低胆固醇水平,但关于这一主题的研究有限;(2)方法:本试验评估了 159 名健康志愿者,他们被随机分为三组:高剂量“弁财天”提取物组(包含 676 毫克儿茶素,组 H)、低剂量“弁财天”提取物组(包含 322 毫克儿茶素,组 L)或不摄入“弁财天”提取物组(组 C)。每组志愿者每天食用含或不含提取物的冰淇淋,持续 12 周,比较其脂质相关参数;(3)结果:与组 L 和组 C 相比,组 H 中载脂蛋白 B (ApoB)含有的凝集素样氧化 LDL 受体-1 配体(LAB)水平显著降低。三组总胆固醇、甘油三酯和 LDL 胆固醇水平无显著差异;(4)结论:含 -甲基化儿茶素的“弁财天”提取物可能有助于预防动脉粥样硬化。