Igarashi Yuko, Obara Taku, Ishikuro Mami, Matsubara Hiroko, Shigihara Michiko, Metoki Hirohito, Kikuya Masahiro, Sameshima Yoichi, Tachibana Hirofumi, Maeda-Yamamoto Mari, Kuriyama Shinichi
Department of Molecular Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Food Nutr Res. 2017 Jun 19;61(1):1334484. doi: 10.1080/16546628.2017.1334484. eCollection 2017.
: Previous studies have reported controversial results for the association between green tea consumption and low-density lipoprotein (LDL)-cholesterol and body weight. : The objective of this trial was to determine the effects of two kinds of green tea on LDL-cholesterol and body weight. : We randomly assigned 151 participants (98 men, 53 women) aged 30-70 years into three groups: Yabukita green tea group, Benifuuki green tea group, or placebo group. Participants consumed 1.8 g/day of green tea extract powder or placebo for 12 weeks. The primary outcomes were LDL-cholesterol level and body weight, and the secondary outcomes were risk factors for cardiovascular disease. : Both Yabukita and Benifuuki green tea significantly lowered LDL-cholesterol. The magnitudes of the lipid-lowering effect of both types of tea were significantly larger than that of placebo. No differences with respect to changes in LDL-cholesterol were observed between the Yabukita and Benifuuki green tea groups. Neither Yabukita nor Benifuuki green tea had any effect on body weight and no difference was observed among groups regarding changes in body weight. : Both Yabukita and Benifuuki green tea lowered LDL-cholesterol, and the lipid-lowering effects of these two green teas were not different. Neither tea lowered body weight.
以往的研究报告了绿茶消费与低密度脂蛋白(LDL)胆固醇及体重之间关联的有争议结果。本试验的目的是确定两种绿茶对LDL胆固醇和体重的影响。我们将151名年龄在30至70岁之间的参与者(98名男性,53名女性)随机分为三组:薮北绿茶组、玉绿绿茶组或安慰剂组。参与者每天饮用1.8克绿茶提取物粉末或安慰剂,持续12周。主要结局是LDL胆固醇水平和体重,次要结局是心血管疾病的危险因素。薮北绿茶和玉绿绿茶均显著降低了LDL胆固醇。两种茶的降脂效果均显著大于安慰剂。薮北绿茶组和玉绿绿茶组之间在LDL胆固醇变化方面未观察到差异。薮北绿茶和玉绿绿茶对体重均无影响,且各组之间在体重变化方面未观察到差异。薮北绿茶和玉绿绿茶均降低了LDL胆固醇,且这两种绿茶的降脂效果没有差异。两种茶均未降低体重。