Arrigoni-Martelli E
Int J Tissue React. 1985;7(6):513-9.
Current available evidence suggesting a role for oxygen free radicals in inflammatory processes is reviewed. The effects of NSAID as scavengers or inhibitors of superoxide anion generation are described. The anti-inflammatory effect of the superoxide dismutase drug version named Orgotein is discussed in relation to its enzymic activity and pharmacokinetics profile.
本文综述了目前关于氧自由基在炎症过程中作用的现有证据。描述了非甾体抗炎药作为超氧阴离子生成清除剂或抑制剂的作用。结合超氧化物歧化酶药物奥古蛋白的酶活性和药代动力学特征,讨论了其抗炎作用。