Greenberg H B, Vo P T, Jones R
J Virol. 1986 Feb;57(2):585-90. doi: 10.1128/JVI.57.2.585-590.1986.
Three distinct strains of murine rotavirus were adapted to growth in cell culture. These strains are genetically related but not identical; they are serotypically heterogeneous. The cultivatable strains were substantially more infectious (approximately 10(6)-fold) for suckling mice than heterologous simian rotaviruses were. Homologous murine rotavirus strains spread from inoculated to uninoculated litter mates and caused diarrhea, while heterologous rotaviruses did not spread and cause illness.
三种不同的鼠轮状病毒毒株经适应后可在细胞培养中生长。这些毒株在基因上相关但并不相同；它们在血清型上具有异质性。可培养的毒株对乳鼠的感染力比异源的猿猴轮状病毒强得多（约10^6倍）。同源的鼠轮状病毒毒株可从接种的乳鼠传播到未接种的同窝乳鼠并引起腹泻，而异源轮状病毒则不会传播和致病。
