Particles-Biology Interactions , Empa, Swiss Federal Laboratories for Materials Science and Technology , Lerchenfeldstrasse 5 , 9014 St. Gallen , Switzerland.
Chem Res Toxicol. 2018 Aug 20;31(8):641-642. doi: 10.1021/acs.chemrestox.8b00177. Epub 2018 Jul 23.
While placental translocation and direct toxicity to fetal tissue of traversed nanomaterials has been a key focus of developmental toxicity studies, the release of maternal and fetal mediators that indirectly interfere with fetal development and health later in life lacks systematic insights and deserves special attention.
虽然胎盘转移和穿过的纳米材料对胎儿组织的直接毒性一直是发育毒性研究的重点，但释放的母体和胎儿介质会间接干扰胎儿在生命后期的发育和健康，这方面缺乏系统的认识，值得特别关注。
