Zhao Yuhuan, Chen Donglai, Chen Yongbing
Department of Cardiothoracic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Zhongguo Fei Ai Za Zhi. 2018 Jul 20;21(7):547-552. doi: 10.3779/j.issn.1009-3419.2018.07.08.
The incidence and mortality of lung cancer rank top in China. One important factor is the occurrence of metastasis. With the development of science technology, the effect of surgical treatment on lung cancer is improved. Moreover, the use of targeted therapy has achieved a new height for the treatment of lung cancer. However, the recurrence rate remains high even the tumor was completely resected at early stage. The occurrence of lymph node micrometastasis is considered as one of the plausible explanations. The difficulty indetecting micrometastasis has been greatly reduced. Although studies dig deeper into the lymph node micrometastasis, there are still some controversies including the selection of surgical procedures, the pathological staging and prognosis about patients with lymph node micrometastasis. This review manages to generalize the latest research progress of lymph node micrometastasis. .
肺癌的发病率和死亡率在中国位居榜首。一个重要因素是转移的发生。随着科学技术的发展，肺癌外科治疗的效果得到改善。此外，靶向治疗的应用使肺癌治疗达到了新高度。然而，即使肿瘤在早期被完全切除，复发率仍然很高。淋巴结微转移的发生被认为是一种合理的解释。检测微转移的难度已大大降低。尽管研究对淋巴结微转移进行了更深入的探讨，但在手术方式的选择、病理分期以及淋巴结微转移患者的预后等方面仍存在一些争议。本综述旨在总结淋巴结微转移的最新研究进展。
