Lin Duoru, Liu Zhenzhen, Cao Qianzhong, Wu Xiaohang, Liu Jinchao, Chen Jingjing, Lin Zhuoling, Li Xiaoyan, Zhang Li, Long Erping, Zhang Xiayin, Wang Jinghui, Wu Dongxuan, Zhao Xutu, Yu Tongyong, Li Jing, Zhou Xiaojia, Wang Lisha, Lin Haotian, Chen Weirong, Liu Yizhi
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
BMJ Open. 2018 Jul 23;8(7):e020234. doi: 10.1136/bmjopen-2017-020234.
To investigate the characteristics of young adult cataract (YAC) patients over a 10-year period.
This observational study included YAC patients aged 18-49 years who were treated surgically for the first time at the Zhongshan Ophthalmic Center in China. YAC patients were analysed and compared with patients with childhood cataract (CC) in January 2005 to December 2014.
During the 10-year period, 515 YAC patients and 2421 inpatients with CC were enrolled. Among the YAC patients, 76.76% (109/142) of unilateral patients had a corrected distance visual acuity (CDVA) better than 20/40 in the healthy eye, whereas only 20.38% (76/373) of bilateral patients had a CDVA better than 20/40 in the eye with better visual acuity. Compared with the CC group, the YAC group had a higher proportion of rural patients (40.40% vs 31.60%, p=0.001). Furthermore, the prevalence of other ocular abnormalities in YAC patients was higher than that in patients with CC (29.71% vs 17.47%, p<0.001).
A large proportion coming from rural areas and a high prevalence of complicated ocular abnormalities may be the most salient characteristics of YAC patients. Strengthening the counselling and screening strategy for cataract and health education for young adults are required especially for those in rural areas.
调查10年间青年成人白内障(YAC)患者的特征。
这项观察性研究纳入了年龄在18 - 49岁首次在中国中山眼科中心接受手术治疗的YAC患者。对YAC患者进行分析,并与2005年1月至2014年12月期间的儿童白内障(CC)患者进行比较。
在这10年期间,共纳入515例YAC患者和2421例CC住院患者。在YAC患者中,单侧患者中76.76%(109/142)健眼的矫正远视力(CDVA)优于20/40,而双侧患者中仅有20.38%(76/373)视力较好眼的CDVA优于20/40。与CC组相比,YAC组农村患者比例更高(40.40%对31.60%,p = 0.001)。此外,YAC患者其他眼部异常的患病率高于CC患者(29.71%对17.47%,p<0.001)。
来自农村地区的比例高以及复杂眼部异常的患病率高可能是YAC患者最显著的特征。尤其对于农村地区的年轻人,需要加强白内障咨询和筛查策略以及健康教育。