Larsson B
Radiat Res Suppl. 1985;8:S310-8.
Between 1956 and 1977, the former synchrocyclotron in Uppsala was used for biological experiments and clinical tests with 185-MeV protons. Therapeutic irradiations have been performed since 1957 by cross-firing with pencil beams through small intracranial structures for the treatment of Parkinsonism and intractable pain and with the spread-out Bragg peak for the treatment of large malignant tumors. Radiological and radiophysical aspects of the use of charged-particle beams were studied in detail. The former accelerator is now being converted to a sector-focusing, frequency-modulated cyclotron, SFSC-200, to permit acceleration of protons up to 200 MeV and other light ions to corresponding energies. Production of spallation neutrons and radionuclides for biomedical uses is expected to start this year. Experiments with charged-particle beams will begin in 1986. This paper presents a discussion of accelerator developments for planned experimental and clinical programs.
1956年至1977年间，乌普萨拉的前同步回旋加速器被用于185兆电子伏特质子的生物学实验和临床试验。自1957年以来，通过用铅笔束交叉照射穿过小的颅内结构来治疗帕金森病和顽固性疼痛，并利用扩展布拉格峰来治疗大型恶性肿瘤，进行了治疗性照射。详细研究了带电粒子束使用的放射学和放射物理学方面。以前的加速器现在正在被改造成一台扇形聚焦、调频回旋加速器，即SFSC - 200，以允许将质子加速到200兆电子伏特，并将其他轻离子加速到相应能量。用于生物医学用途的散裂中子和放射性核素的生产预计今年开始。带电粒子束实验将于1986年开始。本文讨论了为计划中的实验和临床项目而进行的加速器发展情况。
